Publications by authors named "Safura Vardasbi"
Food Chem Toxicol
August 2013
Article Synopsis
- The study investigated the impact of chicory seed extract (CI) on liver fat accumulation (steatosis) in diabetic rats and liver cells (HepG2) using two different experimental setups.
- CI showed promising results by preventing significant liver damage (steatosis-inflammation-fibrosis) when applied simultaneously with the fat-inducing compound, while in non-simultaneous treatment, it improved gene expression linked to fat metabolism.
- CI was found to contain components like caffeic acid and chlorogenic acid and acted as a PPARα agonist, indicating its potential role in addressing different phases of hepatic steatosis.
