Publications by authors named "Safraz Mohammed"

Article Synopsis
  • Large language models like ChatGPT show promise in medical fields, especially clinical neuroscience, with significant developments from OpenAI's GPT-3.5 and GPT-4.
  • The paper explores how ChatGPT can assist in neurosurgery education, including passing medical licensing exams and creating personalized study materials.
  • Caution is advised when using AI tools due to risks like hallucinations and the potential for user overreliance, highlighting the need for careful integration into neurosurgical training.
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Study Design: A pilot, two-group pretest-posttest randomized controlled, single blinded study.

Objective: Our study aim was to compare the changes in low back pain level, fear avoidance, neurodynamic mobility, and function after early versus later exercise intervention following a unilateral lumbar microdiscectomy.

Summary Of Background Data: Exercise is commonly recommended to patients following a lumbar microdiscectomy although controversy remains as to the timing and protocols for exercise intervention.

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Background: Idiopathic normal pressure hydrocephalus (iNPH) is a syndrome that may be reversible by diversion of cerebrospinal fluid (CSF). It is increasingly recognized, and accordingly rates of CSF diversion are increasing despite the absence of level I evidence of efficacy, non-neglible rate of complications and an unclear natural history.

Methods: A total of 349 neurosurgeons, neurologists, geriatricians and neuropsychiatrists rated the perceived efficacy of CSF diversion, the duration of effect of CSF diversion, and the risk-benefit ratio of CSF diversion in iNPH.

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Objectives: The advanced trauma life support (ATLS) course has become the international standard for teaching trauma resuscitation skills. The 2 to 2.5 days course is usually offered as an on-site teaching experience.

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The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization.

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Introduction: In this short illustrated review, we present the case of a frontal lobe schwannoma without cranial nerve or sellar attachment and a sellar schwannoma which mimicked a pituitary adenoma.

Literature Review: We review the rare occurrence of sellar region schwannomas, their clinical presentation, operative management, outcomes, and the possible pathogenesis.

Analysis: The absence of Schwann cells in the central nervous system and the absence of neighboring cranial nerves in these two cases raise issues of the pathogenesis of these rare but curious lesions.

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Objective: Double pituitary adenomas in surgical cases are rarely reported. The incidence in published surgical specimens ranges from 0.4% to 1.

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Objective: The management of aggressive pituitary macroadenomas represents a challenge to neurosurgeons. These tumors are very difficult to treat, owing mainly to their invasive nature, thus resulting in incomplete resections and propensity for recurrence. Multiple surgical procedures (transsphenoidal, transcranial, or a combination of both) are the first line management, followed by radiotherapy and chemotherapy.

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Peliosis is characterised by multiple blood-filled lakes or cavities within parenchymatous organs. Typically found in the liver, spleen, bone marrow and lymph nodes, it has also been described in other organs such as lungs, kidneys, parathyroids and pancreas. The mechanism responsible for the development of peliosis remains unknown.

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