Histomorphometric comparative study of blood vessels and their pattern in follicular cyst, odontogenic keratocyst, and ameloblastoma.

Objective: The present study aimed at assessment and histomorphometric analysis of intratumoral and peritumoral (cystic) blood vessels in odontogenic lesions and their pattern on their clinical behavior by immunohistochemistry and morphometry.

Methods: In a descriptive and analytical cross-sectional study, 45 paraffin blocks of ameloblastoma, odontogenic keratocyst, and follicular cyst were selected and stained immunohistochemically for CD34. In each slide, images of 3 microscopic fields with the highest microvessel density in intratumoral and peritumoral (cystic) areas were captured at 40× magnification with attached camera system.

Quantitative and qualitative analysis of argyrophilic nuclear organizer regions in follicular cyst, keratocystic odontogenic tumor and ameloblastoma.

Background: Multicystic ameloblastoma is a benign odontogenic tumor that exhibits a more aggressive behavior than keratocystic odontogenic tumor (KCOT) and follicular cyst.

Aim: The purpose of the study was to evaluate the proliferation index nuclear organizer regions (NORs) and their distribution among the four odontogenic lesions with known different clinical invasive behavior.

Study And Design: In a descriptive-analytical cross-sectional study, 60 paraffin blocks of odontogenic lesions were prepared for silver nitrate staining.

Microvessel density in follicular cysts, keratocystic odontogenic tumours and ameloblastomas.

Purpose: Multicystic ameloblastoma is a benign epithelial odontogenic tumor that exhibits a more aggressive behavior than follicular cyst and keratocystic odontogenic tumor (KCOT). The aim of this study was to perform an immunohistochemical evaluation of the mean microvessel density (MVD) effect on clinical behavior of odontogenic lesions and to determine whether peritumoral or intratumoral MVD has a more prominent role in clinical behavior of odontogenic lesions.

Methods: In a descriptive-analytic cross-sectional study, 45 paraffin blocks of mentioned lesions were selected and stained immunohistochemically with CD34.

Myofibroblast stromal presence and distribution in squamous epithelial carcinomas, oral dysplasia and hyperkeratosis.

Purpose: Stromal elements play a key role in growth and development of different neoplasms. Myofibroblasts are the major components and occur in stromal tissue during carcinogenesis processes. The purpose of this study was to review the frequency and the distribution pattern of myofibroblasts(αSMA-positive) in the stroma of squamous epithelial carcinoma and to compare values with those for with oral dysplasia and hyperkeratosis.