Apelin and chemerin as promising adipokines in children with type 1 diabetes mellitus.

Background: Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases in children that may be due to micro or macrovascular complications. Diabetic renal disease or nephropathy is a common complication of DM, clinically silent and the only detectable abnormality due to the presence of microalbuminuria.

Subjects And Methods: This study was a case-control study.

Nitric oxide synthase inhibitors protect against brain and liver damage caused by acute malathion intoxication.

Objective: To investigate the effect of N-nitro-l-arginine methyl ester (l-NAME), a non-selective nitric oxide synthase (NOS) inhibitor, and 7-nitroindazole (7-NI), a selective neuronal NOS inhibitor, on oxidative stress and tissue damage in brain and liver and on DNA damage of peripheral blood lymphocytes in malathion intoxicated rats.

Methods: Malathion (150 mg/kg) was given intraperitoneally (i.p.

Novel neuroprotective and hepatoprotective effects of citric acid in acute malathion intoxication.

Objective: To study the effect of citric acid given alone or combined with atropine on brain oxidative stress, neuronal injury, liver damage, and DNA damage of peripheral blood lymphocytes induced in the rat by acute malathion exposure.

Methods: Rats were received intraperitoneal (i.p.