Synergistic Effects of Gentamicin, Cefepime, and Ciprofloxacin on Biofilm of .

Background: is an opportunistic pathogen involved in number of hospital-acquired infections such as catheter-associated urinary tract infections, bacteremia, septicemia, skin infections, and ventilator-associated pneumoniae. Biofilm formation is an important trait implicated in chronic infections, such as cystic fibrosis and chronic pulmonary obstruction. We evaluated effects of gentamicin, cefepime, and ciprofloxacin on biofilm of

Materials And Methods: A total of 266 isolates were collected from the Armed Forces Institute of Pathology (AFIP).

In-vitro Investigation of Antibiotics Efficacy Against Uropathogenic Biofilms and Antibiotic Induced Biofilm Formation at Sub-Minimum Inhibitory Concentration of Ciprofloxacin.

Background: Community-acquired urinary tract infections are associated with significant morbidity, and uropathogenic (UPEC) alone causes 90% of urinary tract infections. This bacterium retains a diverse armament of virulence factors including fimbria, hemolysins, and siderophores production. In a post invasion scenario, formation of intracellular communities mimic biofilm-like characteristics and are linked to recurrent urinary tract infections.