Publications by authors named "Safi Ur Rehman Qamar"
A Machine Learning Approach to Gene Expression in Hypertrophic Cardiomyopathy.
Pharmaceuticals (Basel)
October 2024
Article Synopsis
- Hypertrophic cardiomyopathy (HCM) is a heart condition marked by thickening of the heart muscle, heightening the risk for serious heart issues, and this study looks into the expression of certain genes related to cell death (apoptosis) as potential markers for the disease's progression.
- Blood samples from 93 HCM patients were analyzed using quantitative real-time PCR (qPCR) to assess gene expression and study the relationship between these genes and clinical parameters.
- Results showed that many HCM patients had lower levels of specific apoptosis-regulating genes, whereas BAX and another gene were elevated in a significant number of cases, indicating a possible protective response in the heart, which may be explored further for improving treatment outcomes
The possibility of injectable biomaterials being used in the therapy of peripheral artery disease (PAD) is investigated in this article. We conducted a thorough review of the literature on the use and efficacy of biomaterials (BMs) and drug-coated balloons (DCBs). These BMs included hydrogels, collagen scaffolds, and nanoparticles.
View Article and Find Full Text PDFParticulate Matter-Induced Cardiovascular Dysfunction: A Mechanistic Insight.
Cardiovasc Toxicol
July 2021
Air pollution and particulate matter (PM) are significant factors for adverse health effects most prominently cardiovascular disease (CVD). PM is produced from various sources, which include both natural and anthropogenic. It is composed of biological components, organic compounds, minerals, and metals, which are responsible for inducing inflammation and adverse health effects.
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