Publications by authors named "Saffar Mohammed-Jafar"

Background: hepatitis B virus (HBV) and C virus (HCV) are among the leading causes of mortality worldwide. Health care personnel (HCP) are subjected to increased risk of these infections. Therefore, HBV vaccination and post-vaccination serologic testing (PVST) are recommended for them.

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Objective: To determine the duration of protection conferred by the hepatitis B (HB) vaccination and the necessity of a booster dose.

Methods: Immediately after the initial blood sampling, 252 youths (aged 18.8-20.

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Background And Objective: Antibiotic resistance is increasing, especially in healthcare-associated infections causing significant public health concerns worldwide. National information is required to make appropriate policies, update list of essential drugs for treatment, and evaluate the effects of intervention strategies. A nationwide surveillance of antimicrobial resistant bacteria in nosocomial infections was established in Iran in 2008, so that the data obtained through the surveillance would enable us to construct a database.

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Background: The long-term duration of cell-mediated immunity induced by neonatal hepatitis B virus (HBV) vaccination is unknown.

Objectives: Study was designed to determine the cellular immunity memory status among young adults twenty years after infantile HB immunization.

Patients And Methods: Study subjects were party selected from a recent seroepidemiologic study in young adults, who had been vaccinated against HBV twenty years earlier.

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Background: The epidemiological impact and the duration of protection provided by infant hepatitis B (HB) vaccination are unknown.

Objectives: This study was designed to determine the hepatitis B virus (HBV) infection seromarkers in young adults who have been vaccinated against HBV as the first group of Iranian neonates during 1993 and 1994.

Patients And Methods: We recruited 510 young adults with a history of complete HB vaccination at birth.

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Article Synopsis
  • - This study investigated the age-specific prevalence of hepatitis A virus (HAV) antibodies in 984 individuals aged 1 to 30 in Savadkuh, Iran, revealing an overall seroprevalence rate of 19.20% with a significant increase in rates as age increased.
  • - Participants were categorized into five age groups, and factors such as residency, parental education, and sanitation were analyzed for their impact on seroprevalence, finding no significant differences based on urban or rural residency.
  • - The results suggest a declining trend in HAV immunity among the population, indicating that more children are becoming vulnerable to the infection, signaling a need for updated public health strategies.
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Unlabelled: Urinary tract infections (UTI) are one of the most common infections with an increasing resistance to antimicrobial agents.

Purpose: Empirical initial antibiotic treatment of UTI must rely on susceptible data from local studies.

Materials And Methods: Retrospective analysis of isolated bacteria from children with UTIs was performed at the university hospital during years 2006-2009.

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Objective: To determine age-dependent pertussis specific IgG and IgA antibodies seroprevalence in apparently healthy subjects.

Methods: A total of 595 healthy 1-35-y-old individuals divided into 5 different age groups were selected from Sari district. Antipertussis IgG and IgA antibodies levels were measured quantitatively by ELISA method.

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Objective: The policy of administering the second dose of measles-mumps-rubella (MMR) vaccine (MMR(2)) has recently changed in Iran, at age 1.5 years instead of 4-6 years previously. The effects of such a change on the immune status of the individual are evaluated in this study.

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Background: This study was designed to determine the levels of immunity against diphtheria and tetanus in 110 mothers with/without diphtheria-tetanus toxoid (dT) vaccination during pregnancy and their two-month-old infants before diphtheria-tetanus-pertussis (DTP) immunisation, and also to assess the influence of pre-vaccination passive immunity on the infants' immune response to three doses of DTP vaccination.

Subjects And Methods: Sera from 110 mother-infant pairs before DTP vaccination and from 69 infants after receipt of three doses of DTP vaccine were tested to measure antidiphtheria-antitetanus toxin IgG levels, using a commercial enzyme immunoassay. History of dT toxoid vaccination of mothers at pregnancy was recorded.

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