Diversity of lice and flea- and lice-borne pathogens in free-ranging dogs in Uzbekistan.

Vector-borne diseases pose a significant threat to human and animal health worldwide, with arthropods, including fleas and lice, acting as key vectors for transmitting various pathogens. In Uzbekistan, where millions of domestic dogs coexist with humans, the diversity of vector-borne pathogens carried by ectoparasites remains largely unexplored. This study aimed to investigate the diversity and prevalence of lice and pathogens carried by fleas and lice collected from domestic dogs in Uzbekistan.

Healthcare personnel acceptance and recommendations for influenza vaccine in twelve low- and middle-income countries: A pooled analysis from 2018 to 2020.

Background: Although healthcare personnel (HCP) are targeted for influenza vaccination they typically underutilize vaccines especially in low- and middle-income countries. We explored knowledge, attitudes, and practices of HCP about seasonal influenza vaccines (SIV) to identify factors associated with and modifiable barriers to SIV uptake.

Methods: We pooled individual-level data from cross-sectional surveys about SIV conducted among health workers in 12 low- and middle- income countries during 2018-2020 (i.

Natural radionuclide profiles and radiological risks in soils and rocks of the Koytash-Ugam Range, Uzbekistan.

This investigation quantifies the activity concentrations of natural radionuclides (Ra, Th, and K) in the soils and certain rocks of the Koytash-Ugam Range, Uzbekistan, and assesses their radiological risks. Gamma-spectrometric analysis of soil and rock samples revealed activity concentrations ranging from 456.2 ± 56.

Assessing the effectiveness of fenbendazole supramolecular complexes against schistosomiasis, monieziosis and parabronemosis in sheep.

Helminth infections pose a significant economic threat to livestock production, causing productivity declines and, in severe cases, mortality. Conventional anthelmintics, exemplified by fenbendazole, face challenges related to low solubility and the necessity for high doses. This study explores the potential of supramolecular complexes, created through mechanochemical modifications, to address these limitations.

Evaluation of soil radioactivity in the areas of underground nuclear explosions at the Pomuk gas field site in Uzbekistan.

This study investigates soil radioactivity at the Pomuk gas field in Uzbekistan, a region with history of underground nuclear activity. Using a NaI (Tl) scintillation gamma spectrometer, soil samples were analyzed for concentrations of Th, Ra, K, and Cs. Concentrations were found to be in the range of 19.

Evaluation of radon hazards at the rural settlements of Uzbekistan.

The "passive" sorption detectors based on the activated charcoal together with scintillation spectrometry were utilized to measure radon flux density from the soil surface as well as volumetric activity of indoor radon at the dwellings of rural areas of Uzbekistan. Additionally, gamma dose rates as well as concentrations of natural radionuclides in soil and building materials samples were determined. Based on the values of natural radionuclides, common radiological indices have been calculated.

A case of recurrent human infection in Uzbekistan.

is a zoonotic mosquito-borne filarioid that parasitizes in the subcutaneous tissues of carnivores, that has been incriminated in the great majority of human dirofilariasis cases reported throughout the Old World. From the Republic of Uzbekistan, recent data showed that this parasite is endemic in domestic and wild carnivores. In contrast, information regarding human infection is scarce and mostly outdated, with a single case report being published during the last decades.

Safeness and efficacy of 2-µm handheld thulium laser during microsurgical resection of supratentorial and infratentorial meningiomas: Experience of a single center.

Aims: We performed a retrospective nonrandomized study to analyze the results of a microsurgery of intracranial meningiomas using 2-μm thulium flexible handheld laser fiber (Revolix jr).

Methods: From February 2014 to December 2021, 75 nonconsecutive patients suffering from intracranial meningiomas, admitted in our department, have been operated on with microsurgical technique assisted by 2-μm thulium flexible handheld laser. We have reviewed demographic and clinical data to evaluate safety and efficacy of the technique.

A Survey of Helminths of Dogs in Rural and Urban Areas of Uzbekistan and the Zoonotic Risk to Human Population.

Dogs are very popular pets that can be infected with a wide diversity of endo- and ectoparasites, some of which have zoonotic potential. The aim of the present study was to determine the diversity and prevalence of helminths in rural and urban dogs in Tashkent, Samarkand and Karakalpakstan regions of Uzbekistan. A total of 399 dogs from rural and urban areas were examined by necropsy between November 2016 and March 2022.

A short overview of radioactivity measurement studies in Uzbekistan.

Natural radioactivity is a public health issue that affects people all around the world. Environmental radioactivity accounts for approximately 87% of the radiation dose received by human beings. The primary external source of irradiation to the human body is gamma radiation emitted by naturally occurring radioisotopes such as K and radionuclides from the Th and U families, as well as their decay products, which exist at trace amounts in all ground formations.

Fleas from the Silk Road in Central Asia: identification of Ctenocephalides canis and Ctenocephalides orientis on owned dogs in Uzbekistan using molecular identification and geometric morphometrics.

Background: The Silk Road connected the East and West for over 1500 years. Countries in Central Asia are valuable in addressing the hypothesis that parasites on domestic animals were introduced along the Silk Road. Adult fleas are obligate parasites, having worldwide distribution.

Updates on the distribution and host spectrum of Dirofilaria repens in the Republic of Uzbekistan.

Among the zoonotic mosquito-borne nematodes, Dirofilaria repens and Dirofilaria immitis (Spirurida, Onchocercidae) are highly significant from a public health perspective. While D. immitis is also of major veterinary concern, D.

Endorsement of clinical practice guidelines: Criteria from the College of Family Physicians of Canada.

Objective: To refine the process for endorsement of guidelines and establish the expectations of the College of Family Physicians of Canada (CFPC) regarding the quality and relevance of clinical practice guidelines targeting family physicians and their patients.

Composition Of The Committee: Initially, a group of 6 CFPC staff and selected College members reviewed the previous process for endorsement with the aim of providing a new direction, if needed. The work was then assumed by the Guideline and Knowledge Translation Expert Working Group, a purposefully selected group of 9 family physicians from across Canada with expertise in research, evidence, guidelines, knowledge translation, and continuing professional development and education.

VEGF receptor targeted imaging of angiogenic response to limb ischemia in diabetic vs. non-diabetic Yucatan minipigs.

Background: New therapies to treat diabetic peripheral artery disease (PAD) require target-specific non-invasive imaging modalities to follow efficacy. As a translational study, we performed targeted imaging of receptors for vascular endothelial growth factor (VEGF) in response to anterior femoral artery occlusion (FAO) in Yucatan minipigs and compare the normal response to response in diabetic Yucatan minipigs.

Methods: Eleven Yucatan minipigs, 6 non-diabetic (non-D) and 5 purpose bred diabetic (D) (Sinclair, Auxvasse MO), underwent intravascular total occlusion of the anterior femoral artery (FA).

Rapid assessment methodology in NORM measurements from building materials of Uzbekistan.

Utilizing low cost NaI(Tl) scintillation detector systems we present methodology for the rapid screening of building material samples and the determination of their Radium Equivalent Activity (Ra). Materials from Uzbekistan as a representative developing country have been measured and a correction coefficient for Radium activity is deduced. The use of the correction coefficient offers the possibility to decrease analysis times thus enabling the express measurement of a large quantity of samples.

Soft tissue ossification and condylar cartilage degeneration following TMJ disc perforation in a rabbit pilot study.

Objective: There are limited clinical treatments for temporomandibular joint (TMJ) pathologies, including degenerative disease, disc perforation and heterotopic ossification (HO). One barrier hindering the development of new therapies is that animal models recapitulating TMJ diseases are poorly established. The objective of this study was to develop an animal model for TMJ cartilage degeneration and disc pathology, including disc perforation and soft tissue HO.

[Palivizumab: four seasons in Russia].

In 2010, the Russian Federation (RF) registered palivizumab--innovative drug, based on monoclonal antibodies for passive immunization of seasonal respiratory syncytial virus (RSV) infection in children of disease severe progress risk group, which include primarily premature infants, children with bronchopulmonary dysplasia and hemodynamically significant congenital heart disease. Currently, palivizumab is included in the list of recommended medicines and medical care standards of different countries, including Russia. In the review the results of Russian research on the progress of RSV infection, its epidemiology and immunization experience gained over the 2010-2014 period are summarized in relation to the foreign data.

[Clinical aspects of removable complete dentures].

One of the main goals of modern orthopedic dentistry is the development of high quality removable complete dentures. Some materials used in removable complete denture construction consist of polymethyl methacrylate, which causes of serious pathological process in the tissue of denture's zone, as a result - weakness of adaptation ability of organism and dissatisfaction. Interest increases in production of different types of removable dentures made of thermoplastic materials, which is biocompatible with the organ and tissues of the oral cavity.

[Etiopathogenesis of complication caused by removable full dentures].

The goal of the research was to study the complications caused by removable dentures. For these reason 890 patients were investigated. It was found that the pathologic changes in oral cavity are the results of: poor quality of denture, unfavorable condition before and after prosthesis.

The dying, those who care for them, and how they cope with loneliness.

This study compares the manner in which the dying, their caregivers, and the general population cope with loneliness. The patients were recruited in an oncological hospice in Israel and, despite being on their deathbed, agreed to participate. Thirty-seven cancer-stricken patients, 78 caregivers, and 128 participants From the general population volunteered to take part.

The loneliness experience of the dying and of those who care for them.

Objective: The study compared the qualitative aspects of the loneliness experience of the dying, their caregivers, and the general population.

Method: The patients were recruited in an oncological hospice in Israel, and, despite being on their deathbed, agreed to participate in the study. Thirty-seven cancer-stricken patients, 78 caregivers, and 128 participants from the general population volunteered to partake in the study.

Application of NaI(Tl) detector for measurement of natural radionuclides and (137)Cs in environmental samples: new approach by decomposition of measured spectrum.

An alternative method for determination of activities of natural, technogenic and fallout radionuclides in environmental samples was proposed. The method used a widely available scintillation spectrometer and was based on the decomposition of samples' gamma-spectra into spectral components of separate radionuclide groups with the help of standard sources. The method was tested on water, soil and coal samples and could be successfully used in field (expedition) conditions (without liquid nitrogen for the detector cooling).