Treatment of unprotected left main disease with drug-eluting stents in patients at high risk for coronary artery bypass grafting.

Background: Percutaneous coronary intervention (PCI) for high-grade stenosis of the left main coronary artery with bare-metal stents has been limited by restenosis, and most patients are managed with coronary artery bypass grafting (CABG). Recently, drug-eluting stents (DES) have reduced instent restenosis after PCI, but their role in the treatment of left main disease remains unclear.

Aims: The aim of this study was to determine the outcomes after utilizing DES to treat left main disease.