From May 2022 to January 2023, around 30,000 monkeypox cases were reported in the U.S. and over 86,000 globally, prompting recommendations for the JYNNEOS vaccine for those at increased risk.
The FDA authorized an Emergency Use Authorization (EUA) to allow the vaccine to be given intradermally, using about one-fifth of the subcutaneous dose while still generating an effective immune response.
As of January 31, 2023, over 1.1 million doses of JYNNEOS were administered, achieving approximately 36.7% first dose and 22.7% full vaccination coverage among at-risk individuals, with continued vaccination efforts necessary to prevent potential