Publications by authors named "Safa Majeed"

Article Synopsis
  • Secondary findings (SFs) from genomic sequencing can greatly affect patient health, but guidelines for their clinical investigation are inconsistent, prompting a review of existing policies.
  • The review encompassed 63 SF policies from various international sources, focusing on SFs selection, analysis, and clinical management, and revealed that most guidelines address clinical management while fewer tackle selection and analysis.
  • Although policies scored well for scope and clarity, they fell short in rigor and applicability, indicating a need for improved practices in SFs analysis, clinical validation, and follow-up support to ensure evidence-based care.
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Breast cancer (BC) is the most predominant malignancy in Arab women in the Middle East, and yearly increases in occurrence by 37.5 and mortality rates by 15.2 for every 100,000 in 2019.

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Farmers are continually looking for new, reliable, objective, and non-invasive methods for evaluating the conditions of ewes. Live weight (LW) and body condition score (BCS) are used by farmers as a basis to determine the condition of the animal. Body composition is an important aspect of monitoring animal condition.

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Introduction: Genomic sequencing is increasingly enabling precision care across medical specialties; however, the discovery of genomic 'secondary findings' (SFs) unrelated to the patient's primary indication remains a profuse, unintended consequence. Existing practices within the continuum of SF identification, analysis and management are numerous, inconsistent and sometimes contradictory across health conditions and regions. Final decisions are often at the discretion of the genomic sequencing laboratory, bioinformatician or treating physician.

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Peer mentorship on residency applications has been difficult due to recent public health measures, prompting a shift from in-person events to virtual platforms. To address gaps in career exploration, we created a virtual, non-recorded space that allowed medical students and residents to discuss the Canadian Resident Matching Service (CaRMS) process meaningfully and transparently. Attendees reported a greater understanding of the match process and reduced anxiety after the event.

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Purpose: Small cell lung cancer (SCLC) is an aggressive disease with an overall 5-year survival rate of less than 10%. Treatment for SCLC with cisplatin/etoposide chemotherapy (C/E) ± radiotherapy has changed modestly over several decades. The ubiquitin-proteasome system is an underexplored therapeutic target for SCLC.

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Background: Re-excision due to positive margins following breast-conserving surgery (BCS) negatively affects patient outcomes and healthcare costs. The inability to visualize margin involvement is a significant challenge in BCS. 5-Aminolevulinic acid hydrochloride (5-ALA HCl), a non-fluorescent oral prodrug, causes intracellular accumulation of fluorescent porphyrins in cancer cells.

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The arsenic concentration is an important issue in compost production. The main inputs of a compost factory, including kerbsides, green wastes, food industry wastes, and river weeds are investigated in this study. Also, this study investigated how treated timbers, ashes, and other contamination can impact arsenic concentration in compost production.

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These new experimental methods allow us to image, and quantify, angiogenesis and perivascular cell dynamics in the endosseous healing compartment. As such, the method is capable of providing a new perspective on, and unique information regarding, healing that occurs around orthopedic and dental implants.

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Standard clinical management of extremity soft tissue sarcomas includes surgery with radiation therapy. Wound complications (WCs) arising from treatment may occur due to bacterial infection and tissue breakdown. The ability to detect changes in these parameters during treatment may lead to earlier interventions that mitigate WCs.

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This review paper concentrates on carbon dioxide emissions, discussing its agricultural sources and the possibilities for minimizing emissions from these sources in wheat production in Canterbury, New Zealand. This study was conducted over 35,300 ha of irrigated and dryland wheat fields in Canterbury. Total CO(2) emissions were 1032 kg CO(2)/ha in wheat production.

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