Publications by authors named "Saera Park"

Objective: To develop and validate an artificial intelligence (AI)-based diagnostic system for analysing facial skin images using expert judgements and explore its feasibility for skin ageing research, specifically by evaluating facial skin changes in Korean women of various ages.

Methods: Our AI-based facial skin diagnosis system (Dr. AMORE®) uses facial images of Korean women to analyse wrinkles, pigmentation, skin pores, and other skin red spots.

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Background: The efficacy of non-carbapenems as an empirical antibiotic for extended-spectrum β-lactamases (ESBL)-producing Escherichia coli and Klebsiella pneumoniae bacteremia in children remains controversial. We compared clinical and microbial outcomes according to the types of empirical antibiotics for treating pediatric patients with ESBL-producing E. coli and K.

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Background: As coronavirus disease 2019 (COVID-19) continues, the long-term daily use of masks is increasing. A full year includes the four seasons of spring, summer, autumn, and winter. Skin may have been affected by the seasons and further affected by the use of masks.

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Background: Nowadays, face masks are a crucial part of our daily life. Previous studies on their impact on the skin usually focused on the adverse effects of face masks. Few studies have assessed their influence on skin characteristics.

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Background: Previous studies have demonstrated the possibility of adverse effects of prolonged wearing of personal protective equipment in healthcare workers. However, there are a few studies about the effects on skin characteristics after wearing a mask for non-healthcare workers. In this study, we evaluated the dermatologic effects of wearing a mask on the skin over time.

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Ethical issues in animal toxicity testing have led to the search for alternative methods to determine the skin sensitization potential of cosmetic products. The emergence of ethical testing issues has led to the development of many alternative methods that can reliably estimate skin sensitization potentials. However, a single alternative method may not be able to achieve high predictivity due to the complexity of the skin sensitization mechanism.

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Article Synopsis
  • Exosomes are tiny vesicles released by various cell types that contain genetic materials, indicating their role in communication between cells.
  • Mesenchymal stem cells (MSCs) can migrate to tumors and may influence tumor progression, but the effects of MSC-derived exosomes specifically need more research.
  • In this study, MSC-derived exosomes were found to reduce the expression of a protein called VEGF, which is important for blood vessel formation in tumors, hinting at their potential to inhibit angiogenesis and alter tumor behavior through their molecular content.
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