Non-coding RNAs in oral cancer: Emerging biomarkers and therapeutic frontier.

Around the world, oral cancer (OC) is a major public health problem, resulting in a significant number of deaths each year. Early detection and treatment are crucial for improving patient outcomes. Recent progress in DNA sequencing and transcriptome profiling has revealed extensive non-coding RNAs (ncRNAs) transcription, underscoring their regulatory importance.

Evaluation of the effects of conventional versus laser bleaching techniques on enamel microroughness.

Nowadays, bleaching of the teeth within the dental office is one of the most widespread techniques to correct tooth discoloration. Variability of the materials and techniques accompanied with the trend toward esthetic restorations with minimally invasive approaches are increasing. The use of laser in this regard has also been taken into consideration.

Effects of laser-assisted fluoride therapy with a CO2 laser and Er, Cr:YSGG laser on enamel demineralization.

Purpose: The purpose of this in vitro study was to evaluate the irradiation efficacy of the CO(2) laser and the Er, Cr:YSGG laser-either unassisted or assisted by acidulated phosphate fluoride (APF) treatment-on enamel's acid resistance.

Methods: One hundred twenty enamel samples, obtained from 20 extracted human molars, were randomly assigned to 6 groups as follows: (1) control (C); (2) exposed to acidulated phosphate fluoride (APF) gel (F); (3) Er, Cr:YSGG laser (EL); (4) irradiated with Er, Cr:YSGG laser through APF gel (EL/F); (5) CO(2) laser (CL); and (6) irradiated with CO(2) laser through APF gel (CL/F). The specimens were individually demineralized in an acidified hydroxyethylcellulose system, and the acid resistance was evaluated by determining the calcium ion using atomic absorption spectrometry.