Publications by authors named "Saeid Doaei"

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder with both genetic and environmental risk factors. Imbalanced dietary Intake has recently been proposed as a possible environmental risk factor for ASD. The purpose of this study was to investigate the possible connection between ASD and intake of various carbohydrate types.

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Background: Spontaneous abortion (SA) is reported to be associated with Fat Mass And Obesity-Associated FTO genotype and dietary intake of selenium. This research assessed the potential interactions between the risk of SA, dietary selenium intake, and the FTO rs9939609 polymorphism.

Methods: This case-control study encompassed 192 women who experienced SA and 347 control participants.

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Article Synopsis
  • Spontaneous abortion (SA) is a common complication in pregnancy influenced by genetic factors and maternal nutrition.
  • A study analyzed 192 women with a history of SA versus 347 healthy women, examining the impact of dietary carotenoids and specific gene polymorphisms on the occurrence of SA.
  • The findings revealed that higher intake of β-cryptoxanthin might protect against SA only in women with the TT genotype of the related gene, while no significant links were found for other carotenoids.
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Background: The effects of dairy products on type 2 diabetes mellitus (T2DM) are unclear. Some studies have revealed the beneficial effects, whereas others found harmful effects of dairy products on the risk of T2DM. The objective of the present study was to investigate the association of different types of dairy products with risk of T2DM in Iranian adults.

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  • Autism Spectrum Disorder (ASD) is linked to omega-3 fatty acids insufficiency, prompting a meta-analysis to explore the effects of omega-3 supplementation on ASD symptoms.
  • The review examined multiple studies and found that omega-3 supplementation significantly reduced cluttering speech and hyperactivity in children aged 8 years or younger, particularly when taken for over 14 weeks.
  • However, a lower dosage of omega-3 (≤1000 mg/d) was associated with increased stereotypy and restricted behaviors, suggesting mixed outcomes of supplementation.
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  • The study explores the relationship between dietary choline intake and transient global amnesia (TGA), suggesting a potential protective effect of choline on memory.
  • Researchers analyzed data from 258 TGA patients and 520 non-amnesic participants using a validated food questionnaire, finding a significant inverse relationship between choline intake and TGA occurrence.
  • The findings remained significant even after controlling for various lifestyle factors, indicating the need for more extensive research to further confirm choline's effects on memory function.
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Objectives: Several studies demonstrated the benefits of omega-3 fatty acids supplementation in chronic kidney disease (CKD) patients. The objective of this study was to investigate the effect of omega-3 fatty acids supplementation in body composition, specifically on the lean body mass and fat mass in hemodialysis patients.

Methods: In this randomized, double-blind, placebo-controlled clinical trial, a total of 120 end-stage renal disease (ESRD) patients were randomly allocated into two groups.

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  • The study investigates the link between transient global amnesia (TGA) and dietary intake of vitamin B12, aiming to understand how diet might influence this form of short-term memory loss.
  • Conducted with 258 individuals with TGA and 520 without in Sabzevar, Iran, researchers used a Food Frequency Questionnaire to assess vitamin B12 intake and employed logistic regression models for analysis.
  • Findings indicate that higher dietary intake of vitamin B12 is associated with a lower risk of TGA, suggesting that vitamin B12 deficiency could be a concern for those at risk; further research is recommended to explore this relationship.
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Background: Despite advancements in breast cancer (BC) diagnosis and treatment, it continues to be a serious health concern among women due to its high incidence rate. Thus, prevention strategies in BC are essential. Some nutrients such as vitamin D may play a preventive role against BC through different genes which have a vital role in several pathways.

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Background: The risk of cardiovascular diseases (CVDs) may be influenced by dietary carbohydrates. The aim of this study was to investigate the link between CVDs and the intake of carbohydrates.

Methods: In this cross-sectional study, data was extracted from the Prospective Epidemiologic Research Studies in Iran (PERSIAN) cohort in Sabzevar, Iran.

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  • Chronic kidney disease (CKD) is a serious health problem that can lead to other issues, like anemia, and this study looked at how two types of oils could help patients who are on dialysis.
  • The study involved 120 CKD patients in Iran who took either omega-3 or medium-chain triglyceride (MCT) oil capsules for 8 weeks to see how their iron and other levels changed.
  • The results showed that MCT oil helped to increase iron levels more than omega-3, but other factors like hemoglobin and ferritin levels didn't change much, and more research is needed on MCT oils.
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  • Multiple sclerosis (MS) is a disease that affects the nervous system and can cause serious problems for those who have it.
  • This study looked at how vitamin D levels and certain genes might relate to the risk of developing MS.
  • The findings suggest that a specific gene might lower the risk of MS, but more research is needed to understand the connection with vitamin D.
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  • - The study investigates the link between dietary antioxidant intake and recurrent aphthous stomatitis (RAS), a common oral condition, suggesting that antioxidants may help prevent RAS.
  • - Researchers analyzed data from 144 individuals with RAS and 135 without it, using food frequency questionnaires to evaluate their dietary antioxidant index (DAI).
  • - Findings revealed a significant negative association between RAS occurrence and both zinc's DAI and total DAI score, indicating that a higher antioxidant diet may reduce the risk of RAS.
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Background: Coffee and tea are considered to have some effects on the risk of glioma as one of the most prevalent intracranial malignant tumors in adults. However, the precise effect of coffee and tea consumption on glioma is not obvious. This umbrella review aimed to evaluate the impact of tea and coffee consumption on glioma risk.

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Background: The association of hypertension (HTN) and different types of dietary amino acids is not yet clear. The aim of the present study was to investigate the association of branch chain amino acids (BCAAs) and the prevention of HTN.

Methods: This cross-sectional study was conducted on 4184 people aged 35 to 70 using data from the Sabzevar Persian cohort study in Sabzevar, Iran.

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Background And Aim: Colorectal cancer (CRC) is one of the most prevalent cancers around the world. The link between nutrients and the likelihood of developing CRC remains uncertain. The primary objective of the present study was to investigate the potential connection between dietary intake/dietary supplements and the occurrence of CRC through a literature review.

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  • * Researchers conducted a case-control study with 258 individuals with TGA and 520 without, using a food frequency questionnaire to assess fat intake.
  • * Findings indicate that higher intake of alpha-linolenic acid (a type of omega-3) is linked to a lower risk of TGA, while higher intake of n-6 fatty acids is associated with an increased risk, even after accounting for other factors.
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Background: Coronavirus disease 2019 (COVID-19) results in several complications and mortality in intensive care unit (ICU) patients. Limited studies have investigated the effect of enteral nutrition (EN) on the survival of COVID-19 patients in the ICU. The aim of this study was to investigate the association of EN with biochemical and pathological indices associated with mortality in ICU patients with COVID-19.

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Background: Children with attention deficit hyperactivity disorder (ADHD) may benefit from probiotics and prebiotics, but the effects are unclear. To determine whether probiotics and prebiotics affect children with ADHD, a systematic review was conducted.

Methods: The present systematic review analyzed cohort studies and randomized controlled trials that examined whether prebiotics and probiotics are associated with ADHD.

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Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the relationship between iron and risk of HTN is inconsistent. This study aimed to assess the association between the association of dietary iron intake and HTN in the Iranian population.

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Background: The FTO gene polymorphisms may influence the effects of lifestyle interventions on obesity. The present study aimed to assess the influence of the rs9930506 FTO gene polymorphism on the success of a comprehensive weight loss intervention in male adolescents with overweight and obesity.

Methods: This study was carried out on 96 adolescent boys with overweight and obesity who were randomly assigned to the intervention (n = 53) and control (n = 43) groups.

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Background: Concomitant inflammation may boost the cardiovascular complications in end-stage renal disease (ESRD) patients undergoing hemodialysis (HD). Omega-3 fatty acids may have certain health benefits in HD patients. The aim of this study was to investigate the effects of omega-3 fatty acids supplementation on hematocrit (HCT), hemoglobin (HB) level and platelet (PLT) counts of HD patients.

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Background: Patients undergoing hemodialysis (HD) frequently experience the chronic kidney disease-associated pruritus (CKD-aP).

Objective: The aim of this study was to investigate the effectiveness of omega-3 supplementation in the management of CKD-aP in patients undergoing hemodialysis.

Methods: In this triple blind, randomized clinical trial, the effect of the omega-3 supplement on uremic CKD-aP was assessed in 112 chronic hemodialysis patients at Caspian Hemodialysis Center in Rasht, Iran.

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