Influence of Roll Speed during Roll Compaction and Its Effect on the Prediction of Ribbon Solid Fraction.

Influence of the roll speed () during roll compaction on ribbon, granule, tablet properties and its effect on the prediction of the ribbon solid fraction at-gap is often neglected or controversially discussed. The aim of this study was to investigate the effect of the systematically. Microcrystalline cellulose () and lactose were compressed at several maximum roll pressures () and combinations using a gap-controlled roll compactor.

Clinicopathological Correlation of Microbial Keratitis and Ahead: Is There a Corneal Sepsis?

Microbial, infectious keratitis is a relevant indication for penetrating keratoplasty. The requirement for transplantation results in histopathological examination of the entire thickness of the cornea. Although the clinical diagnosis is not always possible to confirm, pathology can support diagnostic evidence of clinical presentation and pathogenesis.

On the Current Care Situation and Treatment of Ocular Mucous Membrane Pemphigoid in Germany.

Background: Ocular involvement in mucous membrane pemphigoid (MMP) is relatively rare, with a prevalence of 25 cases per million population, equating to approx. 2,100 patients throughout Germany. Diagnosis can be difficult - especially in cases of isolated ocular involvement - and treatment can be complex and lengthy.

Ten-Year Outcome of Glaucoma Drainage Device Surgery After Penetrating Keratoplasty.

Precis: In eyes with intractable glaucoma, drainage devices provide long-term control of intraocular pressure also after penetrating keratoplasty (PK). There is a high incidence of corneal graft failure.

Purpose: To compare very long-term results of eyes with glaucoma drainage device (GDD) after PK.

[The German keratomycosis registry : Initial results of a multicenter survey].

Background And Purpose: Mycotic keratitis is a serious but relatively rare disease. No targeted data collection in Germany existed until the foundation of the German Pilz-Keratitis Register in 2015.

Patients And Methods: The inclusion of retrospective and prospective patients was carried out.

Open globe and penetrating eyelid injuries from fish hooks.

Background: A few case reports have described accidental eye injuries caused by fish hooks. The severity of ocular injuries is dependent on the involved ocular structures. Severe ocular injuries due to fish hooks are rare.

Long-term results of glaucoma drainage device surgery.

Background: To evaluate long-term results of eyes with glaucoma drainage device (GDD).

Methods: We retrospectively reviewed medical records of all patients who underwent GDD placement at our institution between 2001 and 2014. A total of 110 eyes of 90 patients were studied.

Variability of panretinal photocoagulation lesions across physicians and patients. Quantification of diameter and intensity variation.

Background: Photocoagulation lesion intensity relies on the judgement of retinal blanching. Lesions turn out variable due to observer-dependent judgement and time dependency of blanching. We investigated lesion variability per patient and per physician in clinical routine treatments.

[The German Acanthamoeba keratitis register: Initial results of a multicenter study].

Background And Purpose: In September 2011 the cornea section of the German Ophthalmological Society (DOG) established the first German Acanthamoeba keratitis registry. The data of this multicenter survey are being collected, compiled and evaluated at the Department of Ophthalmology at the Saarland University. The aim of this article is to present an intermediate report.

Comprehensive detection, grading, and growth behavior evaluation of subthreshold and low intensity photocoagulation lesions by optical coherence tomographic and infrared image analysis.

Purpose: To correlate the long-term clinical effect of photocoagulation lesions after 6 months, as measured by their retinal damage size, to exposure parameters. We used optical coherence tomographic (OCT)-based lesion classes in order to detect and assess clinically invisible and mild lesions.

Methods: In this prospective study, 488 photocoagulation lesions were imaged in 20 patients.

Photocoagulation in rabbits: optical coherence tomographic lesion classification, wound healing reaction, and retinal temperatures.

Background And Objective: The rabbit is the most common animal model to study retinal photocoagulation lesions. We present a classification of retinal lesions from rabbits, that is based on optical coherence tomographic (OCT) findings, temperature data, and OCT-follow-up data over 3 months.

Materials And Methods: Four hundred eighty-six photocoagulation lesions (modified Zeiss Visulas® 532 nm CW laser, lesion diameter 133 µm, exposure duration 200  milliseconds or variable, power variable) were analyzed from six eyes of three chinchilla gray rabbits.

Correlation with OCT and histology of photocoagulation lesions in patients and rabbits.

Purpose: To examine spectral domain optical coherence tomographic (OCT) and histological images from comparable retinal photocoagulation lesions in rabbits, and to correlate these images with comparable OCT images from patients.

Methods: 508 rabbit lesions were examined by HE-stained paraffin histology. 1019 rabbit lesions versus 236 patient lesions were examined by OCT, all at the time-points 1 hr, 1 week and 4 weeks after photocoagulation.

Correlation of temperature rise and optical coherence tomography characteristics in patient retinal photocoagulation.

We conducted a study to correlate the retinal temperature rise during photocoagulation to the afterward detected tissue effect in optical coherence tomography (OCT). 504 photocoagulation lesions were examined in 20 patients. The retinal temperature increase was determined in real-time during treatment based on thermoelastic tissue expansion which was probed by repetitively applied ns laser pulses.

Temperature-controlled retinal photocoagulation--a step toward automated laser treatment.

Purpose: Retinal laser photocoagulation carries the risk of overtreatment due to effect variation of identically applied lesions. The degree of coagulation depends on the induced temperature increase and on exposure time. We introduce temperature controlled photocoagulation (TCP), which uses optoacoustics to determine individually exposure times necessary to create reproducible lesions.

Selective retina therapy for acute central serous chorioretinopathy.

Aims: To evaluate selective retina therapy (SRT) as a treatment of acute central serous chorioretinopathy.

Methods: 30 eyes of 30 patients with central serous chorioretinopathy of at least a 3 months' duration were recruited. 14 eyes were randomised to an SRT group (Q-switched neodymium-doped yttrium lithium fluoride (Nd:YLF) laser, wavelength 527 nm, t=1.

Implantation of retropupillar iris claw lenses with and without combined penetrating keratoplasty.

Background: For aphakic patients without lens-supporting apparatus, secondary lens implantation can be considered. Literature on retropupillar iris claw lens implantation as a safe alternative to scleral fixated posterior chamber lenses is scarce.

Methods: The study included 22 patients.