Publications by authors named "Saeedeh Shojaeepour"

Article Synopsis
  • The study evaluates laboratory findings in 101 COVID-19 patients compared to 101 healthy individuals, providing insight into how these findings might influence disease progression.
  • The results indicated significant abnormalities in blood parameters among patients, including low white blood cell counts and high levels of C-reactive protein (CRP).
  • The conclusion emphasizes the importance of monitoring these laboratory indicators for early identification and intervention in critically ill COVID-19 patients.
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Background & Objective: Reproductive toxicity of cadmium (Cd) as an environmental toxicant has been proved in animals and humans. Exposure to Cd impairs testes organs and can reduce male fertility. The present study was designed to investigate the spectrum of histopathological changes in testicular tissue focusing on Sertoli cells in rats following Cd intoxication.

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Background: Pentavalent antimonial compounds are currently used to treat leishmaniasis and resistance to these drugs is a serious problem. Multidrug resistance protein is an efflux pump of the cell membrane that expels foreign compounds. This study designed to evaluate the mutations in the multi-drug resistance 1 (MDR1) gene, in biopsy specimens of Leishmania tropica, with high resolution melting (HRM) method.

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Article Synopsis
  • The COVID-19 pandemic has significantly impacted global health, with nearly 2 million deaths and over 90 million infections reported by the end of 2020, prompting extensive research into its biological behavior through autopsy studies and literature reviews.
  • The study analyzed 13 hospitalized patients in Iran with confirmed SARS-CoV-2 infections, utilizing histopathological techniques such as light microscopy and immunohistochemistry to assess tissue damage and inflammatory responses.
  • Findings revealed that cardiovascular disease was the most common co-morbidity, with prevalent symptoms of dyspnea and cough, indicating that the primary viral damage targets endothelial cells, leading to inflammation and a cytokine storm due to leukocyte degeneration.
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Objective: The aim of the present study was to evaluate the demographics, clinical characteristics, fatal dose, the efficacy of treatments, and prognosis in paraquat (PQ) poisoning in the Kerman Province of Iran.

Methods: This analytical cross-sectional study was conducted on 126 PQ poisoned patients who were referred to Afzalipour Hospital during 2006-2015. Demographic variables such as age and gender, signs and symptoms of poisoning, the estimated ingested dosage of PQ, and clinical outcome were extracted from medical records.

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Use of lead-adulterated opium has become one of the major sources of lead poisoning in Iran. This study was designed to assess clinical effects and oxidative stress and its association with GSTM1, GSTT1, NQO1, and ALAD genes polymorphisms and blood lead level (BLL) in lead-adulterated opium users. The oxidative stress status in 192 opium users with lead poisoning symptoms measured and compared with 102 healthy individuals.

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Leiomyosarcoma is a malignant tumor arising from the smooth muscle of any soft tissue. Occurrence of this tumor in the skeletal muscles is rare. A 6-year-old Larry hen was examined because of lameness in one leg.

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Knee joint development and its morphogenetic events have been studied in human, chicken and other animal models and differences have been found in the pattern of the knee joint morphogenesis among the studied species. According to the small number of studies which have focused on the chronology of knee morphogenesis, a "morphogenetic timely pattern" is hard to suggest. Quail is an animal model for which there is no information about knee joint morphogenesis.

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The sheep nasal bot, Oestrus ovis (Diptera: Oestridae), is a cosmopolitan parasite commonly found in sheep and occasionally goats. Rarely a bot will migrate into the sheep brain (false gid). Following the complaint of an animal husbandman about high mortality rate in a sheep herd, the herd was clinically, hematologically, and pathologically examined exactly.

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