Is it time to reconsider the administration of thiamine alone or in combination with vitamin C in critically ill patients? A meta-analysis of clinical trial studies.

Background: Although the effect of thiamine alone or in combination with vitamin C has been studied in multiple trials (RCT and interventional studies), their results are inconsistent. This meta-analysis aimed to assess impact of thiamine administration alone, thiamine in combination with vitamin C, and co-administration of low-dose hydrocortisone, vitamin C and thiamine (HVT) on clinical outcomes in critically ill patients.

Methods And Materials: After electronic searches on PubMed, Scopus, Cochrane Library, and Web of Science databases, initially 3367 papers were found, and 20 interventional studies were included in our analysis.

Effects of select dietary supplements on the prevention and treatment of viral respiratory tract infections: a systematic review of randomized controlled trials.

: Viral respiratory tract infections (RTIs) have been recognized as a global public health burden. Despite current theories about their effectiveness, the true benefits of dietary supplements on the prevention and treatment of viral RTIs remain elusive, due to contradictory reports. Hence, we aimed to evaluate the effectiveness of dietary supplements on the prevention and treatment of viral RTIs.

Association of circulating C-reactive protein and high-sensitivity C-reactive protein with components of sarcopenia: A systematic review and meta-analysis of observational studies.

Background: Sarcopenia, a multi-faceted skeletal muscle disorder in the older population, has poor health outcomes. Some previous observational studies investigated the association between circulating inflammatory markers and sarcopenia components to evaluate chronic inflammation as a risk factor for sarcopenia in the elderly population. Nevertheless, the association between circulating C-reactive protein (CRP) and hs-CRP, as the recognized markers of systemic inflammation and components of sarcopenia, is unclear.

Study of association between beverage consumption pattern and lipid profile in shift workers.

Aims: The circadian system influences on health and metabolic function that can cause raising some risk factor of metabolic syndrome. Few studies have examined data that incorporate the full complexity of daily beverage intake pattern on lipid profiles. The purpose of this study was to investigate relation between daily water and beverage intake of adults working in day or shift work and lipid profile.

Prevalence of metabolic syndrome among Iranian occupational drivers.

Aims: Compared with other members of a society, drivers are under more periodic and constant surveillance due mainly to this fact that their type of work requires them to spend most of their times in a sedentarily position. The recent survey had done to evaluate the prevalence of Met Syn among professional drivers in northeast area of Iran.

Materials And Methods: To evaluate the prevalence of Met Syn among long-haul drivers, 1018 male drivers were studied.

Tumor Necrosis Factor Gene Polymorphisms in Advanced Non-exudative Age-related Macular Degeneration.

Purpose: To investigate tumor necrosis factor (TNF)-α gene polymorphisms in advanced dry-type age-related macular degeneration (AMD) in a population from Northeastern Iran.

Methods: In this case-control study, 50 patients with geographic macular atrophy and 73 gender-matched controls were enrolled. Genomic deoxyribonucleic acid (DNA) was extracted from the peripheral blood.

The ocular hypotensive effect of saffron extract in primary open angle glaucoma: a pilot study.

Background: The progressive nature of glaucoma and its growing incidence make its therapy an important target for research. The role of oxidative damage in the pathogenesis of glaucoma makes antioxidants such as saffron extract an attractive target for potential clinical use. Herein, we evaluate the effect of aqueous saffron extract on intraocular pressure (IOP) in eyes with primary open-angle glaucoma (POAG).

Comparison of Aalen's additive and Cox proportional hazards models for breast cancer survival: analysis of population- based data from British Columbia, Canada.

Background: Regression models for survival data have traditionally been based on the Cox regression model. However, its validity relies heavily on assumption of proportional hazards. Another restriction of the Cox model is insufficiency in dealing with time-varying covariate effects, since the regression coefficients are assumed constant.

A study on chemical properties of groundwater and soil in ophiolitic rocks in Firuzabad, east of Shahrood, Iran: with emphasis to heavy metal contamination.

In order to assess the chemical properties of groundwater and soil in ophiolitic zone of Firuzabad, in east of Shahrood, Iran, 10 soil samples with regard to sensitive points (vicinity to mine, ophiolitic rocks, and villages) and 10 groundwater samples including nine samples from springs, and also one sample from a well in a village of the study area were taken. These samples were analyzed in laboratories using inductively coupled plasma method. The soil samples were also evaluated for grain size.