Developing a novel ultraselective and ultrasensitive label-free direct spectrofluorimetric nanobiosensor for direct highly fast field detection of explosive triacetone triperoxide.

Background: Direct detection of the notorious explosive triacetone triperoxide (TATP) is very difficult because it lacks facile ionization and UV absorbance or fluorescence. Besides, the current indirect methods are time-consuming and need a pre-step for TATP cleavage to hydrogen peroxide. Moreover, they commonly show significant false-positive results in the presence of some camouflage which limits their field applications.

Developing a label-free full-range highly selective pH nanobiosensor using a novel high quantum yield pH-responsive activated-protein-protected gold nanocluster prepared by a novel ultrasonication-protein-assisted procedure.

A novel, label-free, ultra-selective, reproducible, and reversible pH nanobiosensor was developed for analyzing biofluids, food samples, and real water media utilizing a novel activated-protein-protected gold nanocluster with an ultra-narrow emission band, termed as ABSA-AuNCs. The ABSA-AuNCs were synthesized via a novel ultrasonication-protein-assisted procedure, for the first time, using activated bovine serum albumin as both capping and reducing agents. The ABSA-AuNCs revealed a highly narrow symmetric emission spectrum (λ = 330.

A novel selective and sensitive multinanozyme colorimetric method for glutathione detection by using an indamine polymer.

A sensitive and selective novel multinanozyme colorimetric method for glutathione (GSH) detection was developed. MnO-nanozymes can catalyze the oxidation reaction of 3, 3՛-diaminobenzidine (DAB) and produce a brown indamine polymer. In the presence of GSH, this reaction slowly proceeds.

A field-applicable colorimetric assay for notorious explosive triacetone triperoxide through nanozyme-catalyzed irreversible oxidation of 3, 3'-diaminobenzidine.

A field-applicable colorimetric assay for fast detection of notorious explosive triacetone triperoxide (TATP) has been developed through the selective irreversible oxidation of 3, 3'-diaminobenzidine by hydrogen peroxide (HP) liberated during the acidic hydrolysis/degradation of TATP in the presence of MnO nanozymes. The generated HP was detected by probing the absorbance of the product (indamine polymer) of the 3, 3'-diaminobenzidine (DAB) oxidation reaction at 460.0 nm.