Publications by authors named "Saeed Motlaghzadeh"
Background: Bladder cancer (BC) is the tenth most common cancer with the highest mortality rate. Since the etiological role of viral infection in the development of BC is less known, the aim of the present study was to examine the pooled prevalence and possible relationship between viral infection and BC.
Methods: A systematic search of major online databases was conducted to investigate relevant studies.
Metastasis, the dissemination of malignant cells from a primary tumor to secondary sites, poses a catastrophic burden to cancer treatment and is the predominant cause of mortality in cancer patients. Metastasis as one of the main aspects of cancer progression could be strongly under the influence of viral infections. In fact, viruses have been central to modern cancer research and are associated with a great number of cancer cases.
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- Human papillomavirus (HPV) is a common sexually transmitted infection that can lead to various cancers, with this study focusing on its prevalence among women of different ages in Karaj.
- The research analyzed specimens from 2,109 women, finding that 17% tested positive for HPV, with a majority being low-risk, but a significant number also being high-risk, particularly in younger individuals under 30.
- The study identified HPV-16 as the most common genotype and emphasizes the importance of targeted health interventions and vaccination for specific age groups to reduce HPV-related risks.
Expression pattern analysis of the long non-coding RNAs (TINCR, RP11-573D15.8, RP11-156E8.1), and their target genes (AKT1, FOXO1 and MAPK3) in patients with HIV infection, and elite controllers.
Heliyon
May 2024
Elite controllers (ECs) defined as a small subclass of subjects with HIV capable of controlling human immunodeficiency virus (HIV) replication in the lack of antiretroviral treatment. One class of RNA molecules that serve as vital components in the network of HIV-related transcriptional regulation, are long noncoding RNAs (lncRNAs). The critical part that they take is in transcriptional regulation of HIV through monitoring various cellular signaling pathways.
View Article and Find Full Text PDFIntroduction: Human papillomavirus (HPV) presents a potential threat to the onset of carcinogenesis in the cervix, anogenital regions, and oropharynx. HPV encompasses over 200 types, with at least 12 having the potential to cause cancer, impacting the majority of sexually active individuals. In this current research, we explore the occurrence and spread of HPV genotypes.
View Article and Find Full Text PDFAim: This study aimed to investigate the prevalence and any potential association between Epstein-Barr virus (EBV) infection and colorectal cancer (CRC).
Methods: A systematic literature search was performed by finding relevant cross-sectional and case-control studies from main online databases. Heterogeneity, odds ratio (OR), and corresponding 95% confidence interval (CI) were applied to all studies through meta-analysis and forest plots.
Article Synopsis
- Hemodialysis (HD) is a crucial treatment for patients with end-stage renal disease (ESRD), but it carries risks of blood-borne infections, particularly hepatitis B virus (HBV).
- This systematic review analyzed data from 322 datasets, involving over 795,000 patients, finding an overall HBV infection prevalence of 7.32% among HD patients, with notable variations across different geographic regions.
- The findings highlight a significant issue with HBV infections in HD patients globally, suggesting the need for enhanced vaccination strategies as these individuals often struggle to develop adequate immunity.