Publications by authors named "Saeed Moghadam Deymeh"
Article Synopsis
- Bone tissue engineering aims to create a 3D scaffold that mimics natural bone but faces challenges due to the 2D nature of electrospun fibers and their small pore sizes.
- The study involved co-culturing human bone marrow stem cells and endothelial cells in a perfusion bioreactor with improved polycaprolactone scaffolds to promote both bone and blood vessel growth under different flow conditions.
- Results showed higher osteogenesis and calcium content in scaffolds under dynamic vertical flow compared to other conditions, indicating the effectiveness of the bioreactor setup for bone tissue engineering.
Objectives: In this study, gelatin was chosen as a novel sacrificial agent in co-electrospun with polycaprolacton-nanohydroxyapatite (PCL-nHA).
Materials And Methods: After electrospinnig, gelatin was washed with water, and the prepared scaffold was ultrasonicated. Morphological and structural properties of the prepared scaffolds were studied by SEM.