Biochemical Significance of miR-155 and miR-375 as Diagnostic Biomarkers and Their Correlation with the NF-κβ/TNF-α Axis in Breast Cancer.

Serum microRNAs (miRs) have recently been proposed as potential cancer biomarkers for early detection. Thyroid hormones play a crucial role in human health, and their alterations are linked to a range of diseases, such as breast cancer. The relationship between NF-κβ, TNF-α, and non-coding RNAs is an urgent need for clinical trials.

Relationship between hepatitis C virus infection and extrahepatic malignancies.

Aim Of The Study: Hepatitis C virus (HCV) is one of the most common causes of liver-related deaths worldwide. Non-hepatic cancers such as lung and pancreatic cancers have been linked to HCV infection. This study aimed to determine whether HCV seropositivity was related to the development of extrahepatic malignancies and whether this had an impact on patients' survival.

miRNA-1246, HOTAIR, and IL-39 signature as potential diagnostic biomarkers in breast cancer.

The molecular alterations in noncoding RNA can lead to a cellular storm that is correlated to higher mortality and morbidity rates and contributes to the progression and metastasis of cancer. Herein, we aim to evaluate the expression levels and correlations of microRNA-1246 (miR-1246), HOX transcript antisense RNA (HOTAIR), and interleukin-39 (IL-39) in patients with breast cancer (BC). In this study, 130 participants were recruited, including 90 breast cancer patients and 40 healthy control participants.