Publications by authors named "Saeed Ghadimi-Haddadan"
Article Synopsis
- The study focuses on the need for ethnic-specific forensic databases in Iran, specifically examining 600 Turk individuals from northwestern provinces using various STR markers to gather genetic data.
- Results showed deviations from Hardy-Weinberg equilibrium in some loci and highlighted very high combined power of discrimination and exclusion values, indicating their effectiveness in identification tests.
- Comparisons with Azerbaijani and Turkish populations showed no significant differences, while notable variations were found with the Chinese Han population; overall, Iranian populations clustered closely together in genetic analyses.
Alteration in gene expression levels underlies many of the phenotypic differences across species. Because of their highly mutable nature, proximity to the +1 transcription start site (TSS), and the emerging evidence of functional impact on gene expression, core promoter short tandem repeats (STRs) may be considered an ideal source of variation across species. In a genome-scale analysis of the entire Homo sapiens protein-coding genes, we have previously identified core promoters with at least one STR of ≥ 6-repeats, with possible selective advantage in this species.
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