Publications by authors named "Saee Gharpure"

Unlabelled: Biosynthesis of zinc oxide nanoparticles has been reported using leaf (CNL) extract along with estimation of their antimicrobial potential before and after calcination using different micro-organisms. UV-visible spectra of ZnO nanoparticles showed absorption maxima at 383 nm and 363 nm, respectively, with 3.237 eV and 3.

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As traditional cancer therapy is toxic to both normal and cancer cells, there is a need for newer approaches to specifically target cancer cells. ZnO nanoparticles can be promising due their biocompatible nature. However, ZnO nanoparticles have also shown cytotoxicity against mammalian cells in some cases, because of which there is a need for newer synthesis approaches for biocompatible ZnO nanoparticles to be used as carrier molecules in drug delivery applications.

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Zinc oxide nanoparticles have been biosynthesized with the help of leaf and fruit extracts. ZnO nanoparticles were tested for antibacterial activity before and after calcination against Gram positive () as well as Gram negative micro-organisms () within the concentration range 0.625-10 mg/mL with the help of well diffusion technique.

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Zinc oxide nanoparticles were synthesized using different surfactants such as SDS, CTAB, Triton X-100, PVP K-30 and ethylene glycol. ZnO NPs were tested for antibacterial activity before and after calcination against different micro-organisms like and (Gram negative) as well as and (Gram positive). Antibacterial activity was observed in SDScapped ZnO NPs only against .

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Recent COVID-19 pandemic situation caused due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affected global health as well as economics. There is global attention on prevention, diagnosis as well as treatment of COVID-19 infection which would help in easing the current situation. The use of nanotechnology and nanomedicine has been considered to be promising due to its excellent potential in managing various medical issues such as viruses which is a major threat.

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With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties.

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The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms.

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Silver nanoparticles were synthesized by using the white flower extract of Albizia lebbeck as a source of reducing and capping agents. A. lebbeck white flower extract and silver nanoparticles were checked for their antibacterial activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeroginosa and Ba cillus subtilis by using Mueller Hinton agar, nutrient agar and Luria Bertani agar using the well diffusion method.

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Silver nanoparticles synthesized using leaf and fruit extracts which were centrifuged at different speeds (rev/min) were screened for anti-bacterial activity by using four human pathogens namely , (Gram negative) and , (Gram positive). The silver nanoparticles showed good anti-bacterial activity against gram-positive as well as gram-negative bacteria. Nonetheless, silver nanoparticles synthesized using leaf extract has shown pre-dominant anti-bacterial activity rather than fruit extract.

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