Publications by authors named "Sae Yamagishi"
Background: Total small vessel disease (SVD) score is used to measure the burden of SVD.
Objective: This study aimed to clarify the predictive value of total SVD score for incident dementia and functional outcomes in independent outpatients with vascular risk factors.
Methods: We derived data from a Japanese cohort in which patients underwent magnetic resonance imaging and cognitive examinations.
Article Synopsis
- The total small vessel disease (SVD) score evaluates the extent of small vessel disease using four neuroimaging markers, with potential implications for predicting health outcomes like stroke and mortality.
- This study analyzed data from 692 outpatients with vascular risk factors, revealing that higher total SVD scores (≥1) significantly predicted stroke and all-cause death, but not acute coronary syndrome.
- Results indicate the importance of monitoring and managing patients with elevated total SVD scores to prevent strokes and reduce mortality rates, emphasizing the cutoff score of 1 for interventions.
Aims: Increased arterial stiffness is associated with the severity of cerebral small-vessel disease (SVD) and may predict incident dementia. This study investigated the predictive value of brachial-ankle pulse wave velocity (ba-PWV) for dementia and cognitive decline.
Methods: Data were obtained from a Japanese cohort of 478 patients who underwent ba-PWV measurement.