Effectiveness and safety of a thermo-mechanical action device versus thermal pulsation device in the treatment of meibomian gland dysfunction.

Purpose: To evaluate the safety and effectiveness of thermo-mechanical action (Tixel C, Novoxel) compared with thermal pulsation (LipiFlow, Johnson & Johnson) in meibomian gland dysfunction (MGD).

Setting: Private clinics and University clinic, USA.

Design: Prospective, randomized (1:1), evaluator-masked, multicenter study.

Rotational stability and visual performance of aberration-free, hydrophobic acrylic monofocal toric intraocular lens with enhanced material.

Purpose: To evaluate the rotational stability and visual performance of the enVista toric intraocular lens (IOL) (MX60ET) in cataract patients with preexisting astigmatism.

Setting: 6 U.S.

Surgical Outcomes, Ocular Safety and Tolerability of Bio-Interventional Cyclodialysis with Allograft Scleral Reinforcement: Clinical Experience of More than 240 Cases.

To report the surgical safety of reinforced bio-interventional cyclodialysis with scleral allograft reinforcement. This was a consecutive case series of 243 eyes with open-angle glaucoma who underwent a bio-scaffolded cyclodialysis (BSC) procedure for uveoscleral outflow enhancement using allogeneic bio-spacers to maintain patency of the internal filtration conduit. 79% of the eyes underwent concomitant phacoemulsification cataract surgery prior to BSC intervention, while the remaining eyes underwent stand-alone BSC surgery.

Active targeted delivery of theranostic thermo/pH dual-responsive magnetic Janus nanoparticles functionalized with folic acid/fluorescein ligands for enhanced DOX combination therapy of rat glioblastoma.

Doxorubicin (DOX), a chemotherapy drug, has demonstrated limited efficacy against glioblastoma, an aggressive brain tumor with resistance attributed to the blood-brain barrier (BBB). This study aims to overcome this challenge by proposing the targeted delivery of magnetic Janus nanoparticles (MJNPs) functionalized with folic acid ligands, fluorescent dye, and doxorubicin (DOX/MJNPs-FLA). The properties of these nanoparticles were comprehensively evaluated using bio-physiochemical techniques such as Fourier transform infrared (FTIR) spectroscopy, dynamic light scattering (DLS), zeta potential analysis, high-resolution transmission electron microscopy (HR-TEM), vibrating sample magnetometry (VSM), fluorescence microscopy, MTT assay, hemolysis assay, and liver enzyme level evaluation.

Enhanced anti-tumor activity of transferrin/folate dual-targeting magnetic nanoparticles using chemo-thermo therapy on retinoblastoma cancer cells Y79.

Malignant neoplasms are one of the main causes of death, especially in children, on a global scale, despite strenuous efforts made at advancing both diagnostic and therapeutic modalities. In this regard, a new nanocarrier Vincristine (VCR)-loaded Pluronic f127 polymer-coated magnetic nanoparticles conjugated with folic acid and transferrin (PMNP-VCR-FA-TF) were synthesized and characterized by various methods. The cytotoxicity of these nanoparticles was evaluated in vitro and ex vivo conditions.

Cyclic Fatigue Resistance of Five Different Glidepath Files in a Double Curved Artificial Canal.

Introduction: The aim of this study was to examine the cyclic fatigue resistances #16 ProGlider, #15.02 Scout RaCe, #15.03 NeoNiTi GPS, One G and Path-File NiTi glide path files in S-shaped artificial canals.

Evaluation of the Canal Transportation Following Glide Path Preparation with Different Rotary Systems: A Comparative Study.

Objectives: Ideal root canal shaping might be more challenging particularly in cases with severely curved canals or complex anatomical variations. Glide path preparation is suggested as a critical step to achieve ideal canal preparation. The present study is aimed at evaluating transportation at different levels of the canal following glide path preparation by five different path finders.

The Prevalence of Blepharitis in US Eye Care Clinic Patients as Determined by Collarettes: A Pathognomonic Sign.

Purpose: To evaluate the prevalence of blepharitis by its pathognomonic sign, collarettes, in patients presenting for any reason to eye care clinics in the United States.

Patients And Methods: In this retrospective study by 7 investigators at 6 eye care clinics, case records of consecutive patients who underwent a slit-lamp examination, regardless of chief complaint, were reviewed for blepharitis, as identified by the presence of collarettes. Patient characteristics, including age, gender, race, relevant ocular and systemic diagnoses, ocular medications, lid hygiene practices and contact lens wear, were also recorded.

Prevalence of Substance Use among Psychotic Patients and Determining Its Strongest Predictor.

Although comorbidity of psychotic disorders and substance use can lead to increase in mortality, less is known about the outbreak and predictors. Psychotic patients tend to be overlooked during assessment; hence, the possibility of an undertreated or missed condition such as increasing substance use. This investigation aimed to measure the prevalence of substance use in psychotic patients and to survey the powerful predictors.

Evaluation of the Fractured Surface of Five Endodontic Rotary Instruments: A Metallurgical Study.

Introduction: The aim of this study was to compare several metallurgic properties of Neoniti instrument with four other commonly used endodontic rotary files.

Methods And Materials: Neoniti A1 (25/0.08), RaCe (25/0.

Comparison of Cyclic Fatigue Resistance of Five Nickel Titanium Rotary File Systems with Different Manufacturing Techniques.

Objectives: The purpose of this study was to evaluate the resistance to fatigue failure of five different nickel-titanium rotary files in three different curved trajectories.

Materials And Methods: A total of 150 Neoniti A1, RaCe 25.06, Mtwo 25.

Once daily dosing of bromfenac ophthalmic solution 0.09% for postoperative ocular inflammation and pain.

Objective: To evaluate the efficacy and ocular safety of bromfenac ophthalmic solution 0.09% dosed once daily for the treatment of ocular inflammation and pain following cataract extraction with posterior chamber intraocular lens implantation.

Methods: A total of 455 subjects (455 study eyes: 230 bromfenac, 225 placebo) were enrolled in two randomized double-masked, placebo-controlled, clinical trials at 64 ophthalmology clinics in the United States.

Asthma Knowledge among Asthmatic School Students.

Objectives: Bronchial asthma is a common and life threatening problem affecting school children and adolescents. The flare-up of asthma may lead to impaired daily function and absence from school. These complications of bronchial asthma could be influenced by poor knowledge, poor use of inhaler technique, non-compliance and negative attitude toward the illness and drugs.

Isolated tuberculosis of the talus bone.

A 7-year-old boy was referred to us with a 3-month history of swelling and pain on his left ankle. On laboratory evaluation, he only had an elevated erythrocyte sedimentation rate. X-ray showed an extensive lytic lesion of the talus bone.

Refractive stabilization after temporal phacoemulsification with foldable acrylic intraocular lens implantation.

Purpose: To determine the rate of stabilization of refractive error after temporal small incision phacoemulsification with insertion of an acrylic foldable intraocular lens (IOL) (AcrySof MA30).

Setting: A university hospital anterior segment referral practice.

Methods: The records of 100 consecutive patients with good visual potential having phacoemulsification with acrylic IOL implantation who had good visual acuity on the first postoperative day were reviewed.

Orbital lymphangioma: an analysis of 26 patients.

Aim: To evaluate retrospective data on the clinical findings, histological features, radiological diagnosis, and management outcomes in orbital lymphangioma.

Methods: Data on 26 orbital lymphangioma patients managed over 16 years were re-evaluated. The computed tomograph and magnetic resonance scans and histological slides were reviewed.