Diagnosing and finding the disease in medical sciences is a complex procedure. The basic steps involved in finding starts with signs, symptoms, and test. This study is based on the diagnosis of a skin disorder.
View Article and Find Full Text PDFHypertens Pregnancy
December 2023
Objectives: This study aimed to investigate the genetic association between (A1298C) SNP and preeclampsia (PE) in Punjab, Pakistan.
Methods: A sample of 80 pregnant women (40 healthy pregnant women and 40 with PE) was pooled for genotyping A1298C polymorphism by using the tetra-primer amplification refractory mutation system (ARMS) PCR. The Genotypic and allelic assessments were performed using various statistical techniques.
Preeclampsia (PE) presents a major obstetrical problem for mother and fetus which is characterized by the onset of hypertension and proteinuria in formerly normotensive women. Altered folate-mediated one-carbon metabolism is one of the factors for PE development either due to nutritional insufficiencies such as folate deficiency or polymorphisms in genes that code for the key enzymes of the cycle. Commonly, there are four genes in the cycle whose polymorphisms have been described in relation to PE.
View Article and Find Full Text PDFIn this study, the binding tendency of bisnitrophenoxy compounds (BN) having different methylene (-CH-) spacer groups (n = 8-11) with fish sperm double stranded deoxyribonucleic acid (dsDNA) was explored. Cyclic voltammetry (CV) was used to evaluate various kinetic and binding parameters (K, D, K and binding site sizes). Performed electrochemical studies designated strong contact of these symmetric molecules with dsDNA in threading intercalation mode of binding.
View Article and Find Full Text PDFDespite benefits of screening mammography, many South Asian (SA) immigrant women in Canada remain under screened. We aimed to elicit their experiences and beliefs about barriers to mammography and possible solutions. SA immigrant women aged 50 years or over were eligible if they never had a mammogram or had one more than 3 years ago.
View Article and Find Full Text PDFBackground: Anisomelia, or limb-length discrepancy, has disruptive effects on gait, posture, and ambulation. Limb-length discrepancy has been shown to be a factor in stress fractures in the femur and tibia, and the longer limb, a contributing factor in the development of low-back pain, a cause of scoliosis. We sought to determine whether limb-length discrepancy contributes to the frequency and severity of plantar fasciitis.
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