Publications by authors named "Sadia Kafeel"
Praecitrullus fistulosus, commonly known as round gourd or tinda, is a remarkable source of bioactive substances like polyphenols, antioxidants, carotene, magnesium, and vitamin C. It is considered one of the Cucurbitaceae family due to its medicinal features. Plant lectins are carbohydrate-binding proteins that can bind and identify the carbohydrate moieties upon cancerous cells demonstrated some anticancer potentials.
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- - Mangiferin (MGF), derived primarily from the mango tree, exhibits antioxidant and anti-inflammatory properties which may help combat diseases like diabetes, obesity, and various cancers by inhibiting abnormal cell growth.
- - The compound has shown promise in treating lung, liver, ovarian, prostate, breast, stomach, and oral cancers through multiple forms of administration, including nanoparticles and combinations with other drugs to enhance efficacy and bioavailability.
- - MGF acts through various mechanisms such as targeting enzymes and tumor growth factors, promoting apoptosis, and increasing sensitivity to chemotherapy in resistant tumors, though additional research and clinical trials are necessary to fully understand its potential in cancer treatment.