Publications by authors named "Sadia Chaman"
Article Synopsis
- This study analyzed the effects of lyophilized juice from Citrus reticulata on paracetamol-induced toxicity, focusing on its phytochemical makeup and protective properties for the liver and kidneys.
- The research involved 36 rats treated with different doses of paracetamol and lyophilized juice, with blood samples collected at various intervals to assess changes in liver and kidney functions.
- Results showed that the juice, particularly at a dose of 500mg/kg, significantly reduced harmful serum levels, indicating its potential therapeutic effects against liver and kidney damage.
Article Synopsis
- Oral bacterial infections pose significant health risks, especially for diabetic patients, and the rise of antimicrobial resistance is a major concern in treating these infections.
- In a study, researchers explored the effectiveness of combining fluoroquinolone antibiotics (like ciprofloxacin and levofloxacin) with omeprazole, a proton pump inhibitor, which showed enhanced antibacterial activity against identified strains.
- The combination treatment was found to significantly reduce the minimum inhibitory concentration and effectively eliminate biofilms, with a notable bactericidal effect over a 24-hour period, suggesting it could be a promising strategy for treating oral bacterial infections.
Recent advancements in in vitro transcribed mRNA (IVT-mRNA) vaccine manufacturing have attracted considerable interest as advanced methods for combating viral infections. The respiratory mucosa is a primary target for pathogen attack, but traditional intramuscular vaccines are not effective in generating protective ion mucosal surfaces. Mucosal immunization can induce both systemic and mucosal immunity by effectively eliminating microorganisms before their growth and development.
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- Mangifera indica (mango) peels are often discarded but contain important bioactive compounds, including flavonoids and xanthonoids, with potential health benefits, particularly for diabetes management.
- The methanolic extract of the Langra variety of mango showed lower phenol concentrations compared to its chloroform and ethyl acetate fractions, while the Sindhri variety exhibited similar patterns with higher concentrations in the other extracts.
- Both varieties demonstrated significant antidiabetic properties, particularly through α-glucosidase inhibition and preventing the formation of advanced glycation end products, indicating that mango peel waste could be valuable in diabetes treatment.