Dynamics of a fractional order mathematical model for COVID-19 epidemic transmission.

To achieve the aim of immediately halting spread of COVID-19 it is essential to know the dynamic behavior of the virus of intensive level of replication. Simply analyzing experimental data to learn about this disease consumes a lot of effort and cost. Mathematical models may be able to assist in this regard.

Stability Analysis of an Extended SEIR COVID-19 Fractional Model with Vaccination Efficiency.

This work is aimed at presenting a new numerical scheme for epidemic model based on Atangana-Baleanu fractional order derivative in Caputo sense (ABC) to investigate the vaccine efficiency. Our construction of the model is based on the classical SEIR, four compartmental models with an additional compartment V of vaccinated people extending it SEIRV model, for the transmission as well as an effort to cure this infectious disease. The point of disease-free equilibrium is calculated, and the stability analysis of the equilibrium point using the reproduction number is performed.

Modeling the impact of the vaccine on the COVID-19 epidemic transmission via fractional derivative.

To achieve the goal of ceasing the spread of COVID-19 entirely it is essential to understand the dynamical behavior of the proliferation of the virus at an intense level. Studying this disease simply based on experimental analysis is very time consuming and expensive. Mathematical modeling might play a worthy role in this regard.

Finite Difference Method for Time-Space Fractional Advection-Diffusion Equations with Riesz Derivative.

In this article, a numerical scheme is formulated and analysed to solve the time-space fractional advection-diffusion equation, where the Riesz derivative and the Caputo derivative are considered in spatial and temporal directions, respectively. The Riesz space derivative is approximated by the second-order fractional weighted and shifted Grünwald-Letnikov formula. Based on the equivalence between the fractional differential equation and the integral equation, we have transformed the fractional differential equation into an equivalent integral equation.

Use of medical abbreviations and acronyms: knowledge among medical students and postgraduates.

Introduction: Inappropriate use of abbreviations and acronyms in healthcare has become an international patient safety issue. The aim of this study was to assess the knowledge of medical abbreviations and acronyms among residents of the department of medicine at a tertiary-care hospital.

Methods: Internal medicine residents (IMRs), subspecialty residents (SRs) and students were asked to complete a self-administered questionnaire which comprised standard abbreviations used in medicine and its various subspecialties.

Clinical predictors of mortality in hospitalized patients with infective endocarditis at a tertiary care center in Pakistan.

Objective: To evaluate the clinical characteristics and predictors of in-hospital mortality in patients with infective endocarditis at a tertiary care centre in Pakistan.

Methods: The cross-sectional study was conducted at the Aga Khan University Hospital, Karachi, from January 1, 2002, to December 31, 2006, and comprised 84 consecutive patients hospitalised with infective endocarditis,. All patients underwent verification of the diagnosis according to the Modified Duke criterion.

Outcomes in ST elevation Myocardial Infarction; a comparison of a tertiary care center in Pakistan with European centers.

Objectives: To evaluate the clinical characteristics and in hospital outcome data of patients presenting to the Aga Khan University Hospital with ST elevation Myocardial Infarction (STEMI) and its comparison with data from patients enrolled in the European Heart registry for the same duration.

Methods: Data on 296 patients with STEMI was prospectively collected from 1st January 2010, till 31st December 2010 from the cardiology section at the Aga Khan University Hospital. European data was collected on 7485 patients retrieved from the Eurobservational Research programme Acute Coronary Syndrome Registry 2010 for the same duration.

Political riots in Pakistan and stress-induced cardiomyopathy: a case report.

A previously healthy middle-aged lady with no prior risk factors for coronary artery disease presented with chest discomfort and ECG changes suggestive of anterolateral ST elevation myocardial infarction. She had had a stressful event prior to the onset of symptoms in that she had been caught up in a riot and had been exposed to intense mental and physical stress. She was found to have severe global left ventricular dysfunction but coronary artery disease was not discovered on coronary angiography.

Hallucinogen-like actions of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in mice and rats.

Rationale: Few studies have examined the effects of 2,5-dimethoxy-4-(n)-propylthiophenethylamine (2C-T-7) in vivo.

Objectives: 2C-T-7 was tested in a drug-elicited head twitch assay in mice and in several drug discrimination assays in rats; 2C-T-7 was compared to the phenylisopropylamine hallucinogen R(-)-1-(2,5-dimethoxy-4-methylphenyl)-2aminopropane (DOM) in both assays, with or without pretreatment with the selective 5-HT2A antagonist (+)-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenylethyl)]-4-piperidine-methanol (M100907). Finally, the affinity of 2C-T-7 for three distinct 5-HT receptors was determined in rat brain.