Publications by authors named "Sadek K"

In the present investigation, the impact of natural ghee, olive oil and synthetic margarine on the fertility parameters of male rabbits was evaluated by examining semen quality, fertility hormones, antioxidant markers, lipid profile, and liver and kidney functions. Eighty male rabbits were randomly allotted into four groups (20 rabbits each, four replicates/group). The basal diet supplemented the control group; the margarine group was fed a 10% margarine diet, the ghee group was fed a 10% ghee diet, and the olive oil group was fed a 10% olive oil diet.

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Background: Limited data exists regarding the safety and outcomes of combined division of the splenic vessels with the pancreatic parenchyma during laparoscopic distal pancreatectomy (LDP). This study aims to evaluate the combined division technique.

Methods: Patients who underwent LDP for pancreatic cancer from April 2011 to December 2022 were retrospectively reviewed and categorized into the following groups: combined (CV) versus separate (SV) division of the splenic vein; combined (CA) versus separate (SA) division of the splenic artery; and combined (CAV) versus separate (SAV) division of the splenic artery and vein, with or without the pancreatic parenchyma.

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Article Synopsis
  • - The review highlights the harmful effects of bisphenol A (BPA), an industrial chemical, on reproductive health in both humans and animals, focusing on its role in endocrine disruption and hormonal interference.
  • - It consolidates findings from various laboratory animal studies that show BPA exposure negatively impacts reproductive organ performance and induces cell death in testicular cells.
  • - By discussing the mechanisms of BPA-induced apoptosis, the review aims to deepen understanding of how environmental BPA exposure can adversely affect reproductive tissues.
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Objectives: Arab/Middle Eastern North African (MENA) Americans experience high levels of discrimination, which is associated with greater engagement in coping strategies to alleviate the stress. The Coping with Discrimination Scale (CDS; Wei, Alvarez, et al., 2010) remains one of the only measures that assesses responses to discrimination.

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  • Honeybees help us in many ways, not just by making honey; their sting can actually lead to useful medicine due to the special stuff in their venom.
  • Bee venom contains proteins and other molecules that might help treat diseases like cancer and even help heal wounds.
  • This review looks closely at bee venom's makeup, how it can be used safely, and also talks about its traditional uses and benefits for animals, giving a full picture of its potential in medicine.
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Help-seeking attitudes among Arab/Middle Eastern North African (MENA) Americans remain an understudied outcome, despite significant levels of reported mental health concerns. Hierarchical linear regression was used to examine whether Arab/MENA Christians and Muslims' help-seeking attitudes were significantly associated with acculturation, enculturation, and religious orientation. Results indicated that acculturation levels were positively associated with help-seeking attitudes, wherein individuals with higher levels of dominant society immersion were more likely to report more positive attitudes toward help seeking.

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  • The study aimed to evaluate soft tissue changes in patients with retruded chins using three methods: fat augmentation, PEEK augmentation, and sliding genioplasty as a control.
  • A total of 33 patients were divided into the three treatment groups, and both pre-op and post-op assessments were conducted, including the evaluation of patient satisfaction using the Face-Q questionnaire.
  • Results showed that fat augmentation had a significant reduction in soft tissue relapse after 6 months compared to the control, while PEEK results were comparable to the control, indicating that fat augmentation is effective for mild to moderate cases while PEEK provides stable outcomes.
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Graduate teaching assistants (GTAs) play a significant role in higher education and in the education of undergraduate students. Previous research suggests that undergraduate students perceive GTAs differently than faculty instructors, but little has been done to explore the nature of those perceptions. This exploratory study uses self-determination theory to investigate how university students describe the effective teaching practices of GTAs and how those descriptions vary depending on GTA gender, GTA international status, and course domain.

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The purpose of this study was to examine the ways in which depression severity, gender, acculturation, and enculturation are associated with help-seeking attitudes among Arab/Middle Eastern North African (MENA) Americans. A hierarchical linear regression was conducted with a sample of 296 Arab/MENA participants (154 women and 142 men). After controlling for pertinent demographic variables, depression severity was negatively associated with help-seeking.

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Article Synopsis
  • Blue toe syndrome is a condition where the toes turn blue, and it can be caused by different factors.
  • A 38-year-old man from Saudi Arabia had blue toe syndrome and doctors found out he had very high platelet levels because of not having enough iron in his body.
  • He received treatment with pain relief, blood-thinning medicines, fluids, and iron, and got better after a few days.
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Background: Testicular cancer (TC), comprising merely 1% of male neoplasms, holds the distinction of being the most commonly encountered neoplasm among young males.

Recent Findings: Most cases of testicular neoplasms can be classified into two main groups, namely germ cell tumors representing approximately 95% of the cases, and sex cord-stromal tumors accounting for about 5% of the cases. Moreover, its prevalence is on the rise across the globe.

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In this article, a new series of 2-((3,5-disubstituted-2-thioxo-imidazol-1-yl)imino)acenaphthylen-1(2)-ones were synthesized. Imidazole-2-thione with acenaphthylen-one gave a hybrid scaffold that integrated key structural elements essential for DNA damage direct DNA intercalation and inhibition of the topoisomerase II enzyme. All the synthesized compounds were screened to detect their DNA damage using a terbium fluorescent probe.

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Background: Research in health disparities and how they affect underserved populations continues to grow and expand. However, the experiences of Arab/Middle Eastern and North African (MENA) Americans often go unnoticed, and yet, preliminary data suggests there are significant disparities between this population and other groups. The purpose of this scoping review is to examine and synthesize the extent of available literature on health disparities and outcomes for this group.

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Introduction: Tuberculosis (TB) is a major global cause of morbidity and mortality. TB meningitis (TBM) is an implication of systemic dissemination of a primary TB infection that indicates a poorer disease prognosis with various long-term neurological sequelae. Consequently, it is crucial to understand the different clinical presentations and manifestations of such condition.

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Coronavirus disease 2019 (COVID-19) in kidney transplant recipients is a subject of much debate and became of interest to nephrologists amidst the pandemic. The main concerns are the influence of the chronic use of immunosuppressive drugs, the viral-related risk of acute rejection, and the long-term outcome of allograft function. This single-center prospective study included kidney transplant recipients with COVID-19 infection.

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Newcastle disease (ND), avian influenza (AI, H5N8), and infectious bronchitis (IB) are important diseases in the poultry industry and cause significant losses. Vaccination is the most practical method for controlling infectious diseases. To reduce vaccination costs and several disorders in poultry farms, using herbal water supplements for immunomodulation with vaccination is critical to improving or preventing some conditions in the poultry industry.

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Background: While we strive to live with SARS-CoV-2, defining the immune response that leads to recovery rather than severe disease remains highly important. COVID-19 has been associated with inflammation and a profoundly suppressed immune response.

Objective: To study myeloid-derived suppressor cells (MDSCs), which are potent immunosuppressive cells, in SARS-CoV-2 infection.

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Periodontitis is the sixth most common chronic inflammatory disease, destroying the tissues supporting the teeth. There are three distinct stages in periodontitis: infection, inflammation, and tissue destruction, where each stage has its own characteristics and hence its line of treatment. Illuminating the underlying mechanisms of alveolar bone loss is vital in the treatment of periodontitis to allow for subsequent reconstruction of the periodontium.

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Background: Cardiovascular disease (CVD) is the most common cause of death in patients with renal diseases. Cardiac arrhythmia and sudden cardiac death are particularly important, and the burden is higher in patients on hemodialysis. The aim of this study is to compare specific ECG changes as markers of arrhythmias in patients with CKD and patients with end-stage renal disease (ESRD); all without clinically manifest heart disease, with normal control subjects.

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The reproductive effects of several dietary fats (margarine, ghee, and olive oil) on female rabbits were studied. For that purpose, 40 mature female rabbits were designed into four groups of ten rabbits each. Group I was given a control diet, Group II received 10% margarine, Group III received 10% ghee, and Group IV received 10% olive oil; after two months, all rabbits were sacrificed.

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This study was designed to evaluate the potential therapeutic efficacy of vitamin D (Vit D) in averting the harmful effects of type 2 diabetes mellitus (T2D). Forty male Wistar rats were allotted into four groups: (1) the control, (2) Vit D, (3) streptozotocin (STZ), and (4) STZ + Vit D groups. Rats co-treated with Vit D had significantly (p < 0.

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End-stage renal disease is a major health problem with many complications. Previous studies emphasized the relationship of cardiovascular disease and mortality among these patients to dysregulated phosphate homeostasis. Even after successful renal transplantation, the risk is not eliminated.

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Background: Allergic respiratory diseases (ARD) are a highly prevalent health problem affecting infants and children in Yemen. Early infant feeding predisposition to the development of ARD has been a controversial question. The aim of this study is to investigate the association between early feeding before 6 months of age and the development of ARD among children attending Childhood and Maternity Public Hospital (CMPH), Ibb, Yemen Republic.

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