Significant association of polymorphisms (rs28514894, rs2303044) with type 2 diabetes mellitus and laboratory characteristics.

Purpose: To investigate if single-nucleotide polymorphisms (SNPs) in the gene encoding contribute to the development of type-2 diabetes mellitus (T2DM) and whether genotypes of two  polymorphisms, rs28514894 and rs2303044, are associated with laboratory characteristics of T2DM patients.

Method: A total of 900 subjects (450 T2DM cases and 450 healthy subjects) of Iranian ancestry were genotyped for polymorphisms via ARMS-PCR and PCR-RFLP techniques.

Result: Our findings showed a significant correlation between both polymorphisms and increased risk of T2DM.

Determining compliance of ear CT scan with interaoperative findings in deaf children with cochlear implantation.

Introduction: Defecated or impaired hair cell function of the cochlea causes deafness. Cochlear implantation allows transmission of sound information through central auditory pathways using direct electric stimulation of auditory nerve dendrites. Using radiologic imaging, including CT scan is very helpful in selection of candidates and evaluation after implantation.