4-((4-(1-benzyl-2-methyl-4-nitro-1-imidazole-5-yl)piperazine-1-yl)methyl)-1-substituted-1-1,2,3-triazole motifs are designed and synthesized click chemistry. The reaction of 1-(-benzyl- 2-methyl-4-nitro-1-imidazole- 5-yl)-4-(prop-2-yn-1-yl) piperazine as new scaffold with diverse primary azides to selectively produce 1,4-disubstituted-1,2,3-triazoles ---. Physicochemical methods: when H NMR, C NMR, and HRMS are utilized to fully characterize all synthesized compounds.
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