Publications by authors named "Sadayuki Fujishiro"
The gut microbiota was reported to differ between children with autism spectrum disorder (ASD) and typically developing (TD) children, and dysbiosis of the gut microbiota in preterm infants is common. Here, we explored the characteristics of gut microbiota in children born preterm with ASD. We performed 16S rRNA gene sequencing using stool samples from ASD children born preterm and TD children born preterm.
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- Children with severe motor and intellectual disabilities (SMIDs) often have imbalanced gut microbiota due to continuous enteral nutrition, medications, and insufficient exercise.
- A study compared the gut microbiota of 10 children with SMIDs to 19 healthy children, finding lower microbial diversity and less abundance of beneficial bacteria like butyric acid producers in the SMID group.
- The low dietary fiber intake in children with SMIDs was about two-thirds of what is needed for healthy kids, indicating a possible link to the observed dysbiosis; further research with dietary interventions is suggested.
Background: Neonatal acute kidney injury (AKI) is associated with increased mortality and is often assessed with the neonatal modified Kidney Disease: improving Global Outcomes (KDIGO) classification, which uses changes in serum creatinine levels. However, because this classification has many drawbacks, a novel method, the neonatal Risk, Injury, Failure, Loss, and End-Stage Kidney Disease (nRIFLE) classification for diagnosing neonatal AKI according to urine output (UO), was recently proposed. To date, no data on the incidence of AKI according to nRIFLE are available for extremely preterm infants (born at gestational age less than 28 weeks).
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- * Analysis was conducted using 16S rRNA gene sequencing on stool samples from 26 jaundiced neonates and 17 non-jaundiced neonates, all of whom were full-term and breastfed, while controlling for antibiotics and other health conditions.
- * Results showed no difference in overall microbial diversity, but a significant decrease in Bifidobacteriales and increase in Enterococcaceae in jaundiced neonates, suggesting Bifidobacteriaceae may help prevent jaundice
Background: There are no consensus criteria for diagnosing upper urinary tract infections (UTI). Therefore, we conducted a study to assess whether bacterial colony counts of ≥ 10 CFU/ml are optimal for diagnosing upper UTIs among infants.
Methods: This retrospective observational study included 673 patients (<4 months of age) with urine samples obtained by catheterization for bacterial cultures.