Publications by authors named "Sadaruddin A"

Article Synopsis
  • The study assessed blood lead and trace elements (copper and manganese) in traffic police constables in Islamabad to evaluate environmental pollution's impact on metal levels in blood.
  • Results showed that constables had significantly higher mean blood lead (27.27 µg/dl) and manganese levels (21.94 µg/dl) compared to control groups, indicating a strong correlation with vehicle exhaust exposure.
  • The findings suggest that regular exposure to high traffic areas elevates blood lead concentrations, with varying levels of pollution observed between cities like Karachi and Islamabad.
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  • Total serum IgE levels were measured in 219 patients with allergic disorders (asthma, rhinitis, urticaria) compared to 240 healthy individuals, revealing significantly higher IgE levels in allergic patients.
  • Healthy males exhibited higher mean IgE levels (181 IU/ml) than females (99 IU/ml), with levels peaking in those aged 15 to 24 and decreasing after 55.
  • Positive skin tests for allergens were found in a majority of patients with asthma (60%), rhinitis (51%), and urticaria (46%), but the difference in IgE levels between those with positive and negative tests was not statistically significant.
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Blood lead levels were estimated in one hundred and seventy school children, aged 13 to 19 years, residing in Chakshahzad area of Islamabad. The overall mean blood lead level was 2.38 ug/dl (range 0.

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Immunoglobulin levels in 47 children (age 13-20 years) with toxoplasmosis were compared with 46 age and sex matched controls. No significant difference was observed in mean serum immunoglobulin (IgG, IgA, IgM) levels between patients and controls but mean IgM levels were significantly (P) higher in children with acute toxoplasma infection. Total proteins were higher in patients while mean albumin and globulin levels were similar between the two groups.

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  • A study of 270 school children aged 13 to 20 found a 39% prevalence of iron deficiency, with 30% of boys and 54% of girls affected; anemia was present in 17% of boys and 18% of girls.
  • Iron deficiency was more common in adolescent girls than boys, and those with deficiency had significantly lower hemoglobin (Hb) levels compared to peers with adequate iron levels.
  • The findings indicate a need for improved dietary iron availability for lower socio-economic groups, highlighting the importance of regular iron deficiency screening and potential treatment in adolescents.
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Serum calcium, urea and uric acid levels were determined in 100 normal pregnant women and 50 patients with pre-eclampsia. Serum calcium levels were significantly lower and urea and uric acid levels higher in pre-eclampsia. Low levels of calcium were found as early as 28 weeks and can therefore be used for early diagnosis of pre-eclampsia.

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Sera, from 270 school children (age 13 to 20 years) residing in suburbs of Islamabad, were investigated for the presence of toxoplasma gondii, IgG antibodies using the enzyme linked immunosorbent assay (ELISA). The overall prevalence was 17.4%.

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Twenty Six mixed infective and 2 cholesterol gall-stones were stained for cholesterol, calcium, fat and mucoproteins. Calcium and cholesterol were found to be the main constituents of all the calculi. Calcium was found mainly in the centre and mucoprotein in the peripheral layers.

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