Publications by authors named "Sadao Watanabe"

Background: To increase the consultation rate of potential major depressive disorder (MDD) patients, we developed a contact-type fingertip photoplethysmography-based MDD screening system. With the outbreak of SARS-CoV-2, we developed an alternative to contact-type fingertip photoplethysmography: a novel web camera-based contact-free MDD screening system (WCF-MSS) for non-contact measurement of autonomic transient responses induced by a mental task.

Methods: The WCF-MSS measures time-series interbeat intervals (IBI) by monitoring color tone changes in the facial region of interest induced by arterial pulsation using a web camera (1920 × 1080 pixels, 30 frames/s).

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Obstructive pulmonary diseases, such as diffuse panbronchiolitis (DPB), asthma, chronic obstructive pulmonary disease (COPD), and asthma COPD overlap syndrome (ACOS) trigger a severe reaction at some situations. Detecting early airflow limitation caused by diseases above is critical to stop the progression. Thus, there is a need for tools to enable self-screening of early airflow limitation at home.

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A rapid analytical method for residues of the herbicide, glyphosate [N-(phosphonomethyl)glycine], glufosinate [DL-homoalanine-4-yl(methyl)phosphinic acid] and glufosinate metabolite (MPPA: 3-methylphosphinicopropionic acid) in vegetables and fruits was developed by improving the bulletin method of glufosinate. 50 mL of solution extracted with water (corresponding to 2 g of the sample) was loaded on a column packed with 5 mL of anion exchange resin and then the trapped glyphosate, glufosinate and MPPA were eluted with 60 mL of 50% acetic acid. After derivatization with trimethyl orthoacetate, the derivatives were purified and separated on a Florisil cartridge column.

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A rapid analytical method for residues of the herbicide glufosinate [DL-homoalanin-4-yl (methyl)phosphinic acid] and its metabolite (MPPA: 3-methylphosphinicopropionic acid) in soybeans and corns was developed by improving the bulletin method. Fifty mL of solution extracted with water (corresponding to 2 g of the sample) was loaded on a column packed with 5 mL of anion exchange resin, and then the trapped glufosinate and MPPA were eluted with 40 mL of 50% acetic acid. After the derivatization of glufosinate and MPPA with trimethyl orthoacetate, the derivatives were purified and separated on a silica gel cartridge column.

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