Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II.

Human carbonic anhydrases (hCAs) play a central role in various physiological processes in the human body. HCAs catalyze the reversible hydration of CO into HCO, and hence maintains the fluid and pH balance. Overexpression of CA II is associated with diseases, such as glaucoma, and epilepsy.

Investigating seasonal air quality variations consequent to the urban vegetation in the metropolis of Faisalabad, Pakistan.

Urban atmospheric pollution is global problem and and have become increasingly critical in big cities around the world. Issue of toxic emissions has gained significant attention in the scientific community as the release of pollutants into the atmosphere rising continuously. Although, the Pakistani government has started the Pakistan Clean Air Program to control ambient air quality however, the desired air quality levels are yet to be reached.

Detrimental Effects of Induced Soil Compaction on Morphological Adaptation and Physiological Plasticity of Selected Multipurpose Tree Species.

Soil compaction has become a global problem affecting soil worldwide. With an increased population, more demands for food and wood have resulted in intensive cultivation and increased mechanization of our farmlands and irrigated plantations. The use of heavy machinery results in soil compaction, which affects the entire soil ecosystem.

Assessing the effects of limestone dust and lead pollution on the ecophysiology of some selected urban tree species.

Soil and air pollution caused by heavy metals and limestone dust are prevalent in urban environments and they are an alarming threat to the environment and humans. This study was designed to investigate the changes in morphological and physiological traits of three urban tree species seedlings (, and ) under the individual as well as synergetic effects of heavy metal lead (Pb) and limestone dust toxicities. The tree species were grown under controlled environmental conditions with nine treatments consisting of three levels of dust (0, 10, and 20 g) and three levels of Pb contaminated water irrigation (0, 5, and 10 mg L).

State-of-the-art OMICS strategies against toxic effects of heavy metals in plants: A review.

Environmental pollution of heavy metals (HMs), mainly due to anthropogenic activities, has received growing attention in recent decades. HMs, especially the non-essential carcinogenic ones, including chromium (Cr), cadmium (Cd), mercury (Hg), aluminum (Al), lead (Pb), and arsenic (As), have appeared as the most significant air, water, and soil pollutants, which adversely affect the quantity, quality, and security of plant-based food all over the world. Plants exposed to HMs could experience significant decline in growth and yield.

Determining the appropriate level of farmyard manure biochar application in saline soils for three selected farm tree species.

Salinity is a global problem, and almost more than 20% of the total cultivated area of the world is affected by salt stress. Phytoremediation is one of the most suitable practices to combat salinity and recently biochar has showed the tremendous potential to alleviate salt-affected soils and enhance vegetation. Trees improve the soil characteristics by facilitating the leaching of salts and releasing organic acids in soil.

Effect of Organic Amendments in Soil on Physiological and Biochemical Attributes of and under Saline Stress.

(L.) P.J.

Effect of three different types of biochars on eco-physiological response of important agroforestry tree species under salt stress.

Soil reclamation through afforestation along with soil amendments is one of the most suitable practices to combat soil salinity while the use of biochar may have potential to ameliorate salt-affected soils. This study was designed to check effects of different biochars on the physico-chemical properties of soil and characteristics of three important agroforestry trees species: , in saline soils. Farmyard manure biochar (FYMB), sugarcane bagasse biochar (SCB), woodchips biochar (WCB) were applied (6% w/w) to check their effects on plants under saline conditions.

MILAMP: Multiple Instance Prediction of Amyloid Proteins.

Amyloid proteins are implicated in several diseases such as Parkinson's, Alzheimer's, prion diseases, etc. In order to characterize the amyloidogenicity of a given protein, it is important to locate the amyloid forming hotspot regions within the protein as well as to analyze the effects of mutations on these proteins. The biochemical and biological assays used for this purpose can be facilitated by computational means.

Uptake and distribution of minerals and heavy metals in commonly grown leafy vegetable species irrigated with sewage water.

Heavy metal uptake and accumulation behavior in dietary vegetables irrigated with sewage waters is an important issue worldwide. The main objective of this study was to examine and compare the physiological and growth responses of leafy vegetables irrigated with sewage water. A pot experiment was conducted in a wire house with three leafy vegetables, coriander (Coriandrum sativum), mint (Mentha arvensis), and fenugreek (Trigonella foenum), grown under ambient conditions.