Development of the Hiesho (sensitivity of hands or feet to cold) Care Practice Scale for pregnant women.

Aim: Evidence-based indicators are needed to increase the frequency of practicing care for hiesho, which can be a risk factor during childbirth. Such practice will lead to hiesho prevention. This study aimed to develop a Hiesho Care Practice Scale (HCPS) for pregnant women and examine its reliability and validity.

Effects of an individualized nutritional educational program in pregnant women: A randomized controlled trial in Japan.

Aim: To evaluate the effectiveness of an individualized nutritional education program in promoting adequate nutrient intake in pregnant women.

Methods: A stratified randomized controlled trial was conducted. Participants were stratified by factors affecting the primary outcome and randomly assigned to the intervention or control groups.

Effects of web-based learning for nurses on their care for pregnant women with hiesho (sensitivity of hands or feet to cold): A randomized controlled trial.

Aim: Hiesho is a condition characterized by having a cold sensation in the hands or feet (i.e., sensitivity of the hands or feet to cold).

Randomized Controlled Trial to Assess the Effectiveness of a Self-Care Program for Pregnant Women for Relieving Hiesho.

Objective: To assess differences in improvement of hiesho (sensitivity to cold) through a randomized controlled trial (RCT) of one group that used a self-care program (the Home Care Package Program for Relieving Hiesho) and another that did not.

Methods: Participants were pregnant women experiencing hiesho in the 28th to 33rd weeks of pregnancy. The group carried out the intervention program for 4 weeks by wearing leg warmers, performing exercises, and pressing acupuncture points.

Relationship between advanced maternal age, hiesho (sensitivity to cold) and abnormal delivery in Japan.

Background: In Japan, the proportion of women aged 35 and older giving birth has greatly increased in recent years, and maternal age is continuing to increase. Advanced maternal age is a risk factor for abnormal delivery, as is hiesho (sensitivity to cold).

Research Question: This study aimed to assess whether advanced maternal age and hiesho precipitate premature delivery, premature rupture of membranes, weak labor pains, prolonged labor and atonic bleeding.

[Relationship between pregnant women's sensitivity to cold (hiesho) and premature labor assessed using propensity scores for adjusting confounding factors].

Objectives: The purpose of this study is to analyze the influence of sensitivity to cold or hiesho in pregnant Japanese women and to examine the relationship between hiesho and premature labor.

Methods: In this retrospective cohort study in Japanese women after delivery, information for the approximately 12 months between October 19, 2009 and October 8, 2010 was obtained using questionnaire surveys and medical records at 6 hospitals with obstetric and pediatric departments in the Greater Tokyo Metropolitan Area. Further, in this analysis, confounding factors were adjusted by performing analysis of covariance and stratified analysis using propensity scores.

Expression of human ABCB5 confers resistance to taxanes and anthracyclines.

Human ABCB5, an ATP-binding cassette (ABC) transporter gene, has two major mRNA species. One transcript encodes an 812 amino acid polypeptide, ABCB5β, with a transmembrane domain and a nucleotide-binding domain. We isolated the cDNA of another ABCB5 mRNA that encodes a 1257 amino acid polypeptide.

Pregnant women's awareness of sensitivity to cold (hiesho) and body temperature observational study: A comparison of Japanese and Brazilian women.

Background: Sensitivity to cold (hiesho) is a serious health problem in Japan, yet it is minimally understood within Western cultures. The purpose of this study was to clarify the divergence between pregnant Japanese woman living in Japan and pregnant Brazilian women living in Brazil in awareness of hiesho and differences between core body and peripheral temperatures.

Methods: The subjects of this study were 230 pregnant Japanese women living in Japan and 200 pregnant Brazilian women living in Brazil.