Publications by authors named "Sachin S Jogal"
Article Synopsis
- A multicenter phase II trial evaluated the effectiveness of adding vorinostat or bevacizumab to focal radiation therapy (RT) in improving 1-year event-free survival (EFS) for children with newly diagnosed high-grade gliomas (HGGs), compared to the standard treatment of temozolomide.
- Out of 90 patients, the one-year EFS rates were 43.8% for bevacizumab, 41.4% for vorinostat, and 59.3% for temozolomide, with no significant differences among the treatment options.
- The study concluded that combining vorinostat or bevacizumab with RT does not offer superior outcomes compared to temoz
A 17-year-old African American female with human immunodeficiency virus infection presented with an unresectable intracranial neoplasm with mass effect upon the brainstem. Stereotactic biopsy revealed an Epstein-Barr virus (EBV)-associated leiomyosarcoma. Radiation therapy and gemcitabine were used to shrink the mass with the aim to make it surgically resectable.
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