Publications by authors named "Sachin N Tikar"

Background: Aedes aegypti mosquito is responsible for transmitting human diseases like dengue and chikungunya. Personal or space protection with insect repellents is a practical approach to reducing human mosquito contact, thereby minimizing disease transmission. Essential oils are natural volatile substances from plants used as protective measure against blood-sucking mosquitoes.

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Article Synopsis
  • Mosquitoes spread diseases, worsening due to pesticide resistance and environmental harm, leading to a search for plant-based control methods.
  • A study tested six plant species for their effects on Aedes albopictus mosquitoes, using various leaf extracts in different solvents and concentrations.
  • Results showed that extracts from Vernonia cinerea and Callistemon viminalis were effective in killing mosquito larvae, while Prosopis juliflora significantly reduced egg laying, indicating their potential as natural pest control agents.
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Article Synopsis
  • A series of benzimidazole and benzothiazole compounds were synthesized and tested for their ability to kill mosquito larvae, specifically targeting Aedes albopictus and Culex quinquefasciatus.
  • Three compounds demonstrated significant effectiveness, with one compound (10e) achieving complete mortality in both mosquito species.
  • The toxicity levels of compound 10e were measured, showing an LC50 of 6.42 mg/L against Aedes albopictus and 7.01 mg/L against Culex quinquefasciatus over different time periods, with Temephos serving as a reference control.
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The mosquito Culex quinquefasciatus is a ubiquitous species that serves as a major vector for west nile virus and lymphatic filariasis. Ingestion of bloodmeal by females triggers a series of physiological processes in the midgut and also exposes them to infection by these pathogens. The bacteria normally harbored in the midgut are known to influence physiology and can also alter the response to various pathogens.

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