Publications by authors named "Sachin K Kempelingaiah"
Article Synopsis
- Sphingolipids are essential for membrane structure and cellular signaling, with ceramide being a key molecule in this process generated by specific enzymes called ceramide synthases (CerS).
- The small heat shock protein 27 (Hsp27) specifically interacts with and inhibits CerS1, affecting ceramide production; this interaction is crucial for understanding CerS regulation.
- Hsp27's activity influences mitochondrial function and mitophagy, highlighting its role in the cellular response to stress and its significance in managing CerS1-related processes.
