Synopsis of recent research by authors named "Sachie Kitano"
- Sachie Kitano's research primarily focuses on the intersection of autoimmune diseases, particularly Sjögren's syndrome and rheumatoid arthritis, with a particular emphasis on oral health-related quality of life and the molecular mechanisms underlying disease progression.
- Recent findings include the correlation between salivary epidermal growth factor levels and the severity of intraoral manifestations in Sjögren's syndrome, along with the impact of regulatory T cell functions in managing collagen-induced arthritis in mouse models.
- Kitano has utilized various methodologies, including proteomic analyses and immune complex examinations, to explore signaling pathways involving hepatocyte growth factor and sphingosine 1-phosphate in synovial and osteoblast cells, aiming to better understand and potentially improve therapeutic approaches for affected patients.
