Searching for Asymmetric and Heavily Precessing Binary Black Holes in the Gravitational Wave Data from the LIGO Third Observing Run.

Leveraging the features of the GstLAL pipeline, we present the results of a matched filtering search for asymmetric binary black hole systems with heavily misaligned spins in LIGO and Virgo data taken during the third observing run. Our target systems show strong imprints of precession whereas current searches have nonoptimal sensitivity in detecting them. After measuring the sensitivity improvement brought by our search over standard spin-aligned searches, we report the detection of 30 gravitational wave events already discovered in the latest version of the Gravitational Wave Transient Catalog.

Quantum oscillations in the hole-doped cuprates and the confinement of spinons.

A long-standing problem in the study of the under-hole-doped cuprates has been the description of the Fermi surfaces underlying the high magnetic field quantum oscillations, and their connection to the higher temperature pseudogap metal. Harrison and Sebastian [ , 226402 (2011)] proposed that the pseudogap "Fermi arcs" are reconstructed into an electron pocket by field-induced charge density wave order. But computations on such a model [Zhang and Mei, , 47008 (2016)] show an unobserved additional oscillation frequency from a Fermi surface arising from the backsides of the hole pockets completing the Fermi arcs.

Strange Metal and Superconductor in the Two-Dimensional Yukawa-Sachdev-Ye-Kitaev Model.

The two-dimensional Yukawa-Sachdev-Ye-Kitaev (2D-YSYK) model provides a universal theory of quantum phase transitions in metals in the presence of quenched random spatial fluctuations in the local position of the quantum critical point. It has a Fermi surface coupled to a scalar field by spatially random Yukawa interactions. We present full numerical solutions of a self-consistent disorder averaged analysis of the 2D-YSYK model in both the normal and superconducting states, obtaining electronic spectral functions, frequency-dependent conductivity, and superfluid stiffness.

Impact of Acidic and Alkaline Environments on the Surface Morphology of Biodentine and White Mineral Trioxide Aggregate - An In-vitro Study.

Introduction: The physical and chemical properties of calcium silicate cement might be affected due to exposure to acidic or alkaline conditions during clinical use. The present study aimed to evaluate the effect of acidic and alkaline environments on the surface morphology of biodentine (BD) and white mineral trioxide aggregate (wMTA).

Materials And Method: Disc-shaped specimens of BD (n = 30) and wMTA (n = 30) were prepared in a metal mould and wrapped in pieces of gauze.

Use of Orthodontic Mini-Implants in Conjunction with Elastics for Extrusion of Impacted Canines and Correction of Bimaxillary Protrusion.

Orthodontic extrusion of canines, although challenging, can yield excellent results without tooth extraction. Temporary anchorage devices (TADs), involving mini-implants in the alveolar bone, offer stable anchorage via biomechanics. This case report details orthodontic extrusion of bilaterally impacted maxillary canines using TAD mini-implants and elastics.

Gravitational Wave Constraints on Planetary-Mass Primordial Black Holes Using LIGO O3a Data.

Gravitational waves from subsolar mass inspiraling compact objects would provide almost smoking-gun evidence for primordial black holes (PBHs). We perform the first search for inspiraling planetary-mass compact objects in equal-mass and highly asymmetric mass-ratio binaries using data from the first half of the LIGO-Virgo-KAGRA third observing run. Though we do not find any significant candidates, we determine the maximum luminosity distance reachable with our search to be of O(0.

Efficacy of a novel combination of aloe vera gel and pineapple extracts in improving post-extraction pain and healing: A Randomized Controlled Trial.

Background: Absorbable gelatin sponges are able to reduce the incidence of post-extraction complications when soaked with antimicrobial agents. However, the drawbacks associated with the injudicious use of antibiotics warrant the need to explore alternatives to the existing drugs. Aim: The present study aimed to evaluate the efficacy of an absorbable gelatin sponge soaked in a combination of aloe vera and pineapple extracts in reducing post-operative pain and improving the healing rate following dental extractions.

Prevalence and Malignant Transformation Rate of Oral Erythroplakia Worldwide - A Systematic Review.

Background: To determine the characteristics of oral erythroplakia (OE) on a global scale, it is important to analyse and evaluate findings from various studies conducted across multiple geographical locations.

Objectives: This review was conducted to determine the prevalence and malignant transformation rate (MTR) of OE.

Data Sources: A systematic search was performed to identify studies reporting the prevalence and MTR of OE across various databases - PubMed, Web of Science, Google Scholar, Elsevier and ScienceDirect without any restriction for the time of publication.

Magneto-Thermoelectric Transport in Graphene Quantum Dot with Strong Correlations.

Disorder at etched edges of graphene quantum dots (GQD) enables random all-to-all interactions between localized charges in partially filled Landau levels, providing a potential platform to realize the Sachdev-Ye-Kitaev (SYK) model. We use quantum Hall edge states in the graphene electrodes to measure electrical conductance and thermoelectric power across the GQD. In specific temperature ranges, we observe a suppression of electric conductance fluctuations and slowly decreasing thermoelectric power across the GQD with increasing temperature, consistent with recent theory for the SYK regime.

Digital versus Manual Tracing in Cephalometric Analysis: A Systematic Review and Meta-Analysis.

Over the years, various researchers have attempted to compare digital cephalometry with the conventional manual approach. There is a need to comprehensively analyze the findings from the earlier studies and determine the potential advantages and limitations of each method. The present systematic review aimed to compare the accuracy of digital and manual tracing in cephalometric analysis for the identification of skeletal and dental landmarks.

Predictive modelling of stress, anxiety and depression: A network analysis and machine learning study.

Objective: This study assessed predictors of stress, anxiety and depression during the COVID-19 pandemic using a large number of demographic, COVID-19 context and psychological variables.

Methods: Data from 741 adults were drawn from the Boston College daily sleep and well-being survey. Baseline demographics, the long version of the daily surveys and the round one assessment of the survey were utilized for the present study.

The Arabidopsis ARID-HMG DNA-BINDING PROTEIN 15 modulates jasmonic acid signaling by regulating MYC2 during pollen development.

The intricate process of male gametophyte development in flowering plants is regulated by jasmonic acid (JA) signaling. JA signaling initiates with the activation of the basic helix-loop-helix transcription factor (TF), MYC2, leading to the expression of numerous JA-responsive genes during stamen development and pollen maturation. However, the regulation of JA signaling during different stages of male gametophyte development remains less understood.

Radiotherapy Plan Quality Assurance in NRG Oncology Trials for Brain and Head/Neck Cancers: An AI-Enhanced Knowledge-Based Approach.

The quality of radiation therapy (RT) treatment plans directly affects the outcomes of clinical trials. KBP solutions have been utilized in RT plan quality assurance (QA). In this study, we evaluated the quality of RT plans for brain and head/neck cancers enrolled in multi-institutional clinical trials utilizing a KBP approach.

Long-term outcomes of central neurocytoma - an institutional experience.

Introduction: Central Neurocytoma (CN) is a rare, WHO grade 2 brain tumor that predominantly affects young adults. Gross total resection (GTR) is often curative for CNs, but the optimal treatment paradigm including incorporation of RT, following subtotal resection (STR) and for scarcer pediatric cases has yet to be established.

Methods: Patients between 2001 and 2021 with a pathologic diagnosis of CN were reviewed.

Highly biased agonism for GPCR ligands via nanobody tethering.

Ligand-induced activation of G protein-coupled receptors (GPCRs) can initiate signaling through multiple distinct pathways with differing biological and physiological outcomes. There is intense interest in understanding how variation in GPCR ligand structure can be used to promote pathway selective signaling ("biased agonism") with the goal of promoting desirable responses and avoiding deleterious side effects. Here we present an approach in which a conventional peptide ligand for the type 1 parathyroid hormone receptor (PTHR1) is converted from an agonist which induces signaling through all relevant pathways to a compound that is highly selective for a single pathway.

Predictors of salvage therapy for parasagittal meningiomas treated with primary surgery, radiosurgery, or surgery plus adjuvant radiotherapy.

Objective: Parasagittal meningiomas (PM) are treated with primary microsurgery, radiosurgery (SRS), or surgery with adjuvant radiation. We investigated predictors of tumor progression requiring salvage surgery or radiation treatment. We sought to determine whether primary treatment modality, or radiologic, histologic, and clinical variables were associated with tumor progression requiring salvage treatment.

Comparison of Autologous Blood Injection and Dextrose Prolotherapy in the Treatment of Chronic Recurrent Temporomandibular Dislocation: A Randomized Clinical Trial.

Introduction: Prolotherapy is a minimally invasive technique that aims to functionally restore or repair the soft and hard tissues of the TMJ by injecting a stimulant. The present study was conducted to compare the effectiveness of dextrose and autologous blood injection (ABI) as prolotherapy agents in the treatment of patients with chronic recurrent TMJ dislocation (CRTD).

Materials And Method: Thirty-two patients were divided into two groups-ABI and dextrose ( = 16 each).

Localization of overdamped bosonic modes and transport in strange metals.

The strange metal phase of correlated electrons materials was described in a recent theory by a model of a Fermi surface coupled a two-dimensional quantum critical bosonic field with a spatially random Yukawa coupling. With the assumption of self-averaging randomness, similar to that in the Sachdev-Ye-Kitaev model, numerous observed properties of a strange metal were obtained for a wide range of intermediate temperatures, including the linear in temperature resistivity. The Harris criterion implies that spatial fluctuations in the local position of the critical point must dominate at lower temperatures.

Effect of Peri-operative Blood Transfusion on Neurological Outcome Following Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Study.

Background: Anemia is a common complication of aneurysmal subarachnoid hemorrhage and is associated with unfavorable outcomes. Whether the physiological benefits of transfusion for anemia surpass the risk of blood transfusion remains to be determined.

Objectives: The primary outcome was to evaluate the impact of peri-operative blood transfusion on the long-term neurological outcome, assessed by Glasgow Outcome Scale Extended at 3 months.

Adenoid ameloblastoma with dentinoid: A rare hybrid odontogenic tumor.

Background: Adenoid ameloblastoma with dentinoid (AAD) is a hybrid odontogenic tumor comprising histopathological presentation of ameloblastoma (AM) and adenomatoid odontogenic tumor (AOT) along with extracellular dentinoid material.

Case Presentation: A 35-year-old female reported an asymptomatic swelling in the left mandibular posterior region. Histopathological examination revealed composite features of AM with AOT along with dentinoid material, which stained positively with Van Gieson and trichrome stains.

GlioPredictor: a deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning.

Identification of isocitrate dehydrogenase (IDH)-mutant glioma patients at high risk of early progression is critical for radiotherapy treatment planning. Currently tools to stratify risk of early progression are lacking. We sought to identify a combination of molecular markers that could be used to identify patients who may have a greater need for adjuvant radiation therapy machine learning technology.