What Does "Dr. Google" Show Patients Searching for Breast Reconstruction Outcomes Photographs?

Unlabelled: Many women with breast cancer search the internet for photographs of their potential reconstruction outcomes, but little is known about the quality, variety, and relevance of images patients are viewing.

Methods: Breast reconstruction outcome photographs identified by a Google Images search were assessed based on the American Society of Plastic Surgeons/Plastic Surgery Foundation photographic guidelines. Information such as source metadata, breast reconstruction procedure information, and subject demographics was collected from the photographs.

Exploration of novel ligands to target C-C Motif Chemokine Receptor 2 (CCR2) as a promising pharmacological treatment against traumatic brain injury.

It is widely reported that the overexpression of the C-C Motif Chemokine Receptor 2 (CCR2) has negative implications in neuroinflammatory diseases such as traumatic brain injury (TBI), although promising drugs to tackle this have been less forthcoming. As of 2016, only 2 drugs specifically targeting this receptor have made their way to market, with unsuccessful outcome unfortunately, suggesting that the search for more specific and precise ligands is utterly necessary. In this paper we hypothesized that by targeting Glu291, Met295, Trp98, Leu45 and Val189 amino acids, essential in the binding of CCR2 with C-C Motif Chemokine Ligand 2 (CCL2), the endogenous substrate, mitigates its activity in TBI.

Overturned abusive head trauma and shaken baby syndrome convictions in the United States: Prevalence, legal basis, and medical evidence.

Background: Media reports and the Innocence Network assert that wrongful Abusive Head Trauma (AHT)/Shaken Baby Syndrome (SBS) convictions pervade the United States (U.S.) criminal justice system.

Jurors' Gender and Their Fear of False Child Sexual Abuse Accusations Are Related to Their Belief in Child Victims' Allegations.

We developed the first Fear of False Accusations scale, measuring the public's fear of personally being the target of untrue child sexual abuse allegations despite no actual wrongdoing as well as the fear of false allegations being a common problem in society. The scale was statistically reliable within a diverse sample of 964 participants. Several months later, in an ostensibly unrelated mock trial experiment, a subset of the participants assumed the role of mock juror and considered a criminal case involving an accusation of child sexual abuse.

Neurological manifestations of COVID-19: A brief review.

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been predominantly a respiratory manifestation. Currently, with evolving literature, neurological signs are being increasingly recognized. Studies have reported that SARS-CoV-2 affects all aspects of the nervous system including the central nervous system (CNS), peripheral nervous system (PNS) and the muscular system as well.

A hybrid ensemble-based technique for predicting drug-target interactions.

Drug-target interaction is the intercommunication between chemical drugs and target proteins to produce any kind of change in the human body. The laboratory experiments conducted to recognize these potential intercommunications are costly and tedious. Various computational methods have been established recently, including the chemogenomic approach for identifying drug-target intercommunication, that integrates the chemical data of the drugs and the genomic properties of the proteins for identifying the interactions between them.

A comprehensive review of computational techniques for the prediction of drug side effects.

Drugs refer to the chemical compounds that are consumed by the human body and induce a change by interacting with the protein targets. The drugs may induce favorable or unfavorable changes in the human body. The unfavorable changes that are elicited by the drugs in the human body are known as drug side effects.

Fabrication of LaFeO and rGO-LaFeO microspheres based gas sensors for detection of NO and CO.

In the present report, gas sensing devices based on LaFeO and rGO-LaFeO were fabricated by a photolithography technique. The X-ray diffraction, Raman spectra and FT-IR results confirm the formation of a perovskite phase and composite. XPS and TEM give the chemical compositions for both products.

Linking etiology with diabetes mellitus: Inferences from a matched case-control study.

Background: Diabetes is one of the most rapidly increasing disease in the contemporary context. Its rapid global rise indicates that its cause are possibly closely associated with the routine lifestyle and eating habits. Diabetes is also possibly the medical condition, which presents with a preclinical phase having a possibility of reversal if its possible causes can be seriously understood and eliminated.

A comprehensive review of feature based methods for drug target interaction prediction.

Drug target interaction is a prominent research area in the field of drug discovery. It refers to the recognition of interactions between chemical compounds and the protein targets in the human body. Wet lab experiments to identify these interactions are expensive as well as time consuming.

Guidelines for the peri-operative care of people with dementia: Guidelines from the Association of Anaesthetists.

Ageing populations have greater incidences of dementia. People with dementia present for emergency and, increasingly, elective surgery, but are poorly served by the lack of available guidance on their peri-operative management, particularly relating to pharmacological, medico-legal, environmental and attitudinal considerations. These guidelines seek to deliver such guidance, by providing information for peri-operative care providers about dementia pathophysiology, specific difficulties anaesthetising patients with dementia, medication interactions, organisational and medico-legal factors, pre-, intra- and postoperative care considerations, training, sources of further information and care quality improvement tools.

Measurement of the Neutrino Mixing Angle θ_{23} in NOvA.

This Letter reports new results on muon neutrino disappearance from NOvA, using a 14 kton detector equivalent exposure of 6.05×10^{20} protons on target from the NuMI beam at the Fermi National Accelerator Laboratory. The measurement probes the muon-tau symmetry hypothesis that requires maximal θ_{23} mixing (θ_{23}=π/4).

First Measurement of Electron Neutrino Appearance in NOvA.

We report results from the first search for ν_{μ}→ν_{e} transitions by the NOvA experiment. In an exposure equivalent to 2.74×10^{20} protons on target in the upgraded NuMI beam at Fermilab, we observe 6 events in the Far Detector, compared to a background expectation of 0.

A novel model to test accuracy and reproducibility of MDCT scan protocols for coronary calcium in vivo.

Objectives: We compared the accuracy and reliability of prospectively triggered, retrospectively ECG gated, and non-gated CT image reconstruction for measurements of coronary artery calcification (CAC) in vivo using a novel animal model.

Materials And Methods: In six Yorkshire farm pigs, prefabricated chains of cortical bone fragments were sutured over the epicardial bed of the major coronary arteries. Using a 4-slice MDCT scanner, each animal was imaged with two different protocols: sequential acquisition with prospective ECG triggering, and spiral acquisition with retrospectively ECG gated image reconstruction- non-gated reconstructions were also generated from these latter scans.

Emergency medicine and air rescue in India: future perspectives.

76.7% of Indian population lives in rural areas. About 160,000 primary health care centres and subcentres, established all over the country, are responsible for the emergency care in the countryside.

Structure of pescaproside E, a fatty acid glycoside from Ipomoea pescaprae.

Three fatty acid glycosides, designated pescaprosides A, B, and E, have been isolated from Ipomoea pescaprae (family Convolvulaceae). Chemical studies on pescaproside E, the major product, led to its characterisation as a pentaglycoside of 11-hydroxyhexadecanoic acid. Its sugar chain was esterified with 2-methylbutanoic and lauric acids.

Dodonic Acid, A New Diterpenoid from Dodonaea viscosa1.

The aerial parts of DODONAEA VISCOSA afforded a new diterpenoid, dodonic acid, the structure and stereochemistry of which have been established by chemical and spectroscopic means.

Anorectic effect of SK & F 38393, a new dopamine agonist in rats.

Anorectics are clinically used in the management of obesity to accept dietary restriction through decreased desire of food intake. The present study, indicates that the drug SK & F 38393 a dopamine agonist given to albino rats at the doses of 1 mg/kg and 5 mg/kg caused decreased food intake. Central side effects observed with amphetamine and other related drugs were not observed with this drug.

Trigeminal nerve stimulation: short latency somatosensory evoked potentials.

We have devised a technique to measure trigeminal somatosensory evoked potentials, stimulating the mentalis nerve at the mandibular foramen and recording the evoked early potential on the scalp at 3.2 msec. The early potential was easily recognized in all normal subjects and on the asymptomatic side of patients with facial pain.

Generalized, bilaterally synchronous bursts of slow waves in the EEG.

Forty-two patients who had bursts of spontaneous, bilaterally synchronous slow waves during the waking state in an otherwise normal EEG were compared with 42 age-matched control subjects with normal EEGs. The study group had a significantly higher incidence of diffuse encephalopathy than did the control group. They also had a higher incidence of alterations of consciousness.