Publications by authors named "Sabry A S Sadek"
Toxoplasmosis remains a prevalent parasitic zoonosis worldwide, raising public health concerns. The global information available regarding the role of camels in the epidemiology of is still limited. This study aimed to assess the seroprevalence of in dromedary camels () from northern and southern Egypt.
View Article and Find Full Text PDFis an opportunistic intracellular protozoon which may cause severe disease in the immunocompromised patients. Unfortunately, the majority of treatments on the market work against tachyzoites in the acute infection but can't affect tissue cysts in the chronic phase. So, this study aimed to evaluate the effect of bee venom (BV) loaded metal organic frameworks (MOFs) nanoparticles (NPs) for the treatment of chronic murine toxoplasmosis.
View Article and Find Full Text PDFParasitological, Molecular, and Histopathological Investigation of the Potential Activity of Propolis and Wheat Germ Oil against Acute Toxoplasmosis in Mice.
Pharmaceutics
February 2023
Article Synopsis
- - Toxoplasmosis is a widespread parasitic disease affecting all vertebrates, and current treatments have significant side effects, sparking interest in alternative herbal remedies like propolis and wheat germ oil (WGO).
- - A study involving 50 albino mice evaluated the effectiveness of these herbal treatments on acute toxoplasmosis by comparing them to a control group and analyzing the effects on various organs through several examinations.
- - Results showed that both propolis and WGO significantly reduced parasitic load and improved organ health, with the best results observed in mice treated with a combination of both substances, highlighting their potential as alternative therapies.
Wheat Germ Oil and Propolis Decrease Parasite Burden and Restore Marked Histopathological Changes in Liver and Lung in Mice with Chronic Toxoplasmosis.
Animals (Basel)
November 2022
Toxoplasmosis is a parasitic zoonotic disease with a worldwide distribution. Its effects can be critical in immunocompromised patients. However, there is a limited availability of effective, low-toxicity drugs against this disease, particularly in its chronic form.
View Article and Find Full Text PDFArticle Synopsis
- Campylobacteriosis is a common bacterial foodborne illness primarily linked to animal products like poultry and milk; this study aimed to assess the prevalence and virulence of Campylobacter isolates in Egypt.
- A total of 1299 samples from chickens, milk, and human stool were tested, revealing that 38.09% of human samples, 37.84% of chicken samples, and 8.5% of milk samples were positive for Campylobacter, predominantly the species C. jejuni.
- The study found that all isolates carried the virulence gene, with a high prevalence of the cytolethal distending toxin B gene, indicating a significant public health risk and the need for improved food safety measures.