Honeybee Venom: A Potential Source of Anticancer Components.

Cancer is a deadly disease that has claimed millions of lives worldwide. Traditional cancer treatments, such as chemotherapy and radiation, have been used for many years but have become less favored due to drug resistance, lack of tumor selectivity, high costs, and various side effects, such as fatigue and hair loss. Many studies have reported that animal venoms, such as those from snakes, scorpions, and bees, contain bioactive peptides that can be synthesized into anti-- cancer peptides (ACPs), which offer a potential alternative to traditional cancer therapies.

study of potential SARS-CoV-2 antagonist from .

Objectives: In this study, we implemented a structure-based virtual screening protocol in search of natural bioactive compounds in that could inhibit the viral M.

Methods: A library of twelve main bioactive compounds in was created from PubChem database by minimizing ligand structure in PyRx software to increase the ligand flexibility. Molecular docking studies were performed by targeting M (PDB ID: 6lu7) via Discovery Studio Visualiser and PyRx platforms.