Publications by authors named "Sabrina Tessier"
Nirsevimab Effectiveness Against Cases of Respiratory Syncytial Virus Bronchiolitis Hospitalised in Paediatric Intensive Care Units in France, September 2023-January 2024.
Influenza Other Respir Viruses
June 2024
Article Synopsis
- In September 2023, France launched a national immunization campaign using nirsevimab, a monoclonal antibody targeting respiratory syncytial virus (RSV).
- A case-control study was conducted with 288 infants from 20 pediatric intensive care units (PICUs) to assess the effectiveness of nirsevimab against severe RSV bronchiolitis.
- The study found nirsevimab to have an effectiveness of 75.9% in the main analysis, with higher estimates of 80.6% and 80.4% in sensitivity analyses, confirming its efficacy observed in previous clinical trials.
Article Synopsis
- Enteric yersiniosis is a common food-borne illness in Europe, primarily monitored in France by the Yersinia National Reference Laboratory, which has been using whole genome sequencing (WGS) since 2017 to analyze isolates.
- From 2017 to 2021, a total of 7,642 strains were characterized, revealing the majority (87.2%) were from the most common pathogenic lineage (lineage 4).
- A new typing method called core genome Multilocus Sequence Typing (cgMLST) was developed to enhance surveillance, resulting in the identification of 419 clusters of pathogenic isolates, which aids in understanding outbreaks and cases more effectively.
The PRALIMAP (PRomotion de l'ALIMentation et de l'Activité Physique) trial highlights the effectiveness of implementing a screening strategy in high schools to prevent overweight/obesity among adolescents. The strategy comprises three steps: i) body measurements to detect overweight/obese adolescents, ii) a medical interview with each adolescent identified to discuss the findings, and iii) an adapted care management consisting of seven group educational sessions. A process evaluation was conducted in the PRALIMAP trial to assess the effective implementation of the screening strategy activities, and the participation of adolescents and school professionals in them, from a qualitative and a quantitative point of view.
View Article and Find Full Text PDFBackground: Given the increasing prevalence of obesity among youth over the past decade, prevention has become an international public health priority.
Purpose: To evaluate the 2-year effectiveness of three strategies aimed at preventing overweight and obesity among adolescents in a high school setting.
Design: PRomotion de l'ALIMentation et de l'Activité Physique (PRALIMAP) is a school-based RCT.
Background: Some studies have investigated the association between body mass index (BMI) and health-related quality of life (HRQoL) among adolescents, but their results have been discrepant and few paid attention to the role of gender. The present investigation aimed to assess the relationship between weight status and HRQoL in adolescents and to verify whether it was similar in boys and girls.
Methods: Five thousand two hundred and twenty six adolescents aged 14 to 18 years were included in the PRomotion de l'ALIMentation et de l'Activité Physique (PRALIMAP) trial, a 2x2x2 factorial cluster randomized trial performed in 24 high schools in France.
Background: Given the increase in overweight and obesity prevalence in adolescents in the last decade, effective prevention strategies for these conditions in adolescents are urgently needed. The PRALIMAP (Promotion de l'ALImentation et de l'Activité Physique) trial aims to evaluate the effectiveness for these conditions of 3 health promotion strategies--educational, screening and environmental--applied singly or in combination in high schools over a 2-year intervention period.
Methods: PRALIMAP is a stratified 2 × 2 × 2 factorial cluster randomised controlled trial including 24 state high schools in Lorraine, northeastern France, in 2 waves: 8 schools in 2006 (wave 1) and 16 in 2007 (wave 2).
Background: This study investigates the association of perceived environment and meeting the current public health recommendations (PHRs) for physical activity (PA) and examines the role of body mass index (BMI) in this relation.
Methods: A total of 4231 subjects (>or=18 years), from seven European countries, were involved in a cross-sectional survey. PA was measured by the International PA Questionnaire, and specific questions about perceived environment for PA were added.
Objective: This study aimed to assess whether changes in leisure-time physical activity over 3 years are associated with changes in health-related quality of life.
Method: Among the adults enrolled in the Supplementation en Vitamines et Minéraux Antioxidants study in France, 3891 completed the Modifiable Activity Questionnaire to assess leisure-time physical activity and the Medical Outcomes Study 36-item Short-Form to assess health-related quality of life in 1998 and 2001. Multivariate analyses involving logistic and linear regressions determined the association between changes in leisure-time physical activity and changes in health-related quality of life.
Background: There are few data on the relationship between health-related quality of life (HRQoL) and leisure time physical activity (LTPA) in the general population. We investigated the relationships of meeting public health recommendations (PHR) for moderate and vigorous physical activity with HRQoL in French adult subjects.
Methods: LTPA and HRQoL were assessed in 1998 in 2333 men and 3321 women from the SU.
The aim of this study was to determine noninvasive predictive factors of significant liver fibrosis in patients with increased serum aminotransferases associated with features of metabolic syndrome (abdominal obesity, systemic hypertension, fasting hyperglycemia, and dyslipidemia). One hundred seventy-three patients were prospectively examined, regardless of alcohol consumption. Biometric, metabolic, and hepatic biochemical variables were tested for association with fibrosis assessed on liver biopsy according to the Metavir score system.
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