Publications by authors named "Sabrina Gregoire"
Article Synopsis
- - Complex associating with SET1 (COMPASS) is a histone methyltransferase that includes the regulatory subunit Cfp1, which plays a key role in recognizing the methylation of histone H3 at lysine 4 (H3K4me3).
- - Research shows that while the yeast analog Spp1 has a specific structure for H3K4me3 recognition, metazoan Cfp1 lacks certain structural elements, leading to a unique binding configuration for H3K4me3.
- - Mutations in Cfp1 linked to cancer disrupt its ability to bind H3K4me3, suggesting these mutations may affect important epigenetic signaling pathways.
