Publications by authors named "Sabrina Brounts"

Objective: To evaluate the radiation dose to personnel locations during simulated head and limb scans with a novel equine standing CT (sCT) system.

Methods: Measurements were made with the use of a helical fan beam sCT system (Equina; Asto CT Inc). Scatter radiation was measured in different positions in the sCT room to mimic the location of the control operator, horse handler, and lead rope handler during simulated equine head and limb imaging.

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Article Synopsis
  • - The study investigates how effective digital radiographs (DR) and standing computed tomography (sCT) are in assessing the risk of condylar stress fractures in Thoroughbred racehorses, which can lead to catastrophic injuries.
  • - Four observers analyzed images of 31 horses, focusing on bone structure changes, and found that while both imaging methods had high specificity, the sensitivity for detecting structural changes was relatively low.
  • - Results indicated that sCT provided better repeatability and reliability for risk assessments compared to DR, particularly for identifying horses at high risk of injury.
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Objective: To describe the feasibility of a novel thread-transecting technique for the tenotomy of the equine deep digital flexor tendon (DDFT).

Animals: 39 equine distal limb specimens.

Methods: Under ultrasonographic guidance, a surgical thread was percutaneously placed around the DDFT through 2 needle punctures (lateral and medial) using a Tuohy needle in equine limbs (22 forelimbs, 17 hindlimbs).

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Article Synopsis
  • Spontaneous tendon and ligament ruptures, particularly degenerative suspensory ligament desmitis (DSLD), are common in equine species, especially affecting breeds like the Peruvian Horse, suggesting a genetic link.
  • A study involving 183 Peruvian Horses identified 151 risk-related genetic markers (SNPs) associated with DSLD and highlighted heritability estimates around 0.22, indicating a moderate genetic influence.
  • The research discovered significant genomic regions on several chromosomes, pinpointed 66 genes with selection signatures, and indicated that pathways like proteoglycan metabolism and hedgehog signaling may play roles in DSLD risk, with strong predictive performance achieved using genomic modeling.
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Objective: To develop and describe a minimally invasive, ultrasound-guided, percutaneous technique for the desmotomy of equine palmar/plantar annular ligaments (PALs) using a transecting thread.

Study Design: Ex vivo study.

Sample Population: Twenty-one normal equine distal limb specimens.

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Objective: To evaluate the diagnostic capabilities of a novel helical fan beam CT system used for imaging of horses with clinical problems of the head and neck.

Animals: 120 horses.

Procedures: Medical records were reviewed of horses presented for CT of the head or neck at 2 university hospitals.

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Objective: To evaluate the diagnostic capabilities of a novel helical fan beam CT system used for imaging of horses with a range of clinical distal limb problems.

Animals: 167 horses.

Procedures: Medical records were reviewed of horses presented for CT of the distal limb at 2 university-based veterinary hospitals.

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Degenerative suspensory ligament desmitis is a progressive idiopathic condition that leads to scarring and rupture of suspensory ligament fibers in multiple limbs in horses. The prevalence of degenerative suspensory ligament desmitis is breed related. Risk is high in the Peruvian Horse, whereas pony and draft breeds have low breed risk.

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Background: There are no reports describing the long-term outcome of sport horses undergoing unilateral mandibular condylectomy with meniscectomy (UMC) for treatment for severe temporomandibular joint (TMJ) disease (TMD). Whether horses undergoing UMC require a specialized diet, can return to riding with a bit, or return to intended function after surgery is unknown.

Objective: To determine the long-term outcome of horses undergoing UMC for treatment of severe TMD.

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A 2-year-old Holstein heifer presented to a university teaching hospital with an apical tooth infection of the right mandibular third molar. A standing oral extraction technique was attempted for tooth removal; however, the molar could not be delivered intact. A tooth sectioning technique was performed, and the affected molar was successfully delivered.

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Objective: To evaluate with CT the characteristics of brain tissue disruption and skull damage in cadaveric heads of adult horses caused by each of 6 firearm-ammunition combinations applied at a novel anatomic aiming point.

Sample: 53 equine cadaveric heads.

Procedures: Heads placed to simulate that of a standing horse were shot with 1 of 6 firearm-ammunition combinations applied at an aiming point along the external sagittal crest of the head where the 2 temporalis muscles form an inverted V.

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Mammalian platelets participate in the immediate tissue injury response by initiating coagulation and further promoting tissue injury mitigation and repair. The latter properties are deployed following platelet release of presynthetized morphogens, cytokines, and growth and chemotactic factors, which launch a tissue regenerative, angiogenic, and anti-inflammatory program. Several blood-derived biologic products, like platelet-rich plasma (PRP) and platelet lysate (PL), are currently on the market to allow proper healing and tissue regeneration.

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Castration of pet pigs is becoming a commonly performed procedure. However, little information is available regarding surgical techniques and complications. Medical records of 106 pet pigs admitted to 3 teaching hospitals for castration were reviewed.

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This study compared post-operative complications and survival in horses with right dorsal displacement of the large colon (RDD) and horses with other non-strangulating large colon (NSLC) lesions. Data were obtained from medical records of horses undergoing exploratory laparotomy from 2000 to 2016 and from owner questionnaire. Of 137 horses that fitted the inclusion criteria, 67 (49%) had RDD and 70 (51%) had NSLC lesions.

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Case Description: A 6-year-old castrated male Bactrian camel was evaluated because of a 14hour history of oliguria and stranguria that progressed to anuria.

Clinical Findings: Perineal urethral pulsations and intermittent tail flagging with no accompanying urination were observed. Ultrasonography of the urethra revealed multiple hyperechoic foci with shadowing artifact indicative of calculi present in the penile urethra distal to the sigmoid flexure.

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OBJECTIVE To assess the effects of sedation on results of acoustoelastography of the superficial digital flexor tendons (SDFTs) in clinically normal horses. ANIMALS 27 clinically normal horses. PROCEDURES For each horse, the pathology index (PI) for the SDFT of each thoracic limb was determined by use of acoustoelastography at 4 locations (5, 10, 15, and 20 cm distal to the accessory carpal bone).

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Equine degenerative suspensory ligament desmitis (DSLD) in Peruvian Paso horses typically presents at 7-15 years and is characterized by lameness, focal disorganization of collagen fibrils, and chondroid deposition in the body of the ligament. With the aim of developing a test for disease risk (that can be used to screen horses before breeding) we have quantified the expression of 76 TGFβ-signaling target genes in adipose-derived stromal fibroblasts (ADSCs) from six DSLD-affected and five unaffected Paso horses. Remarkably, 35 of the genes showed lower expression (p<0.

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Estimation of cranial cruciate ligament (CrCL) structural properties in client-owned dogs with incipient cruciate rupture would be advantageous. The objective of this study was to determine whether magnetic resonance imaging (MRI) measurement of normal CrCL volume in an ex-vivo canine model predicts structural properties. Stifles from eight dogs underwent 3.

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The purpose of this study was to assess the potential for ultrasound shear wave elastography (SWE) to measure tissue elasticity and ultimate stress in both intact and healing tendons. The lateral gastrocnemius (Achilles) tendons of 41 New Zealand white rabbits were surgically severed and repaired with growth factor coated sutures. SWE imaging was used to measure shear wave speed (SWS) in both the medial and lateral tendons pre-surgery, and at 2 and 4 wk post-surgery.

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Objective: To compare the in vitro biomechanical properties of a novel subcuticular stapling device to current methods of abdominal skin closure for equine abdominal surgery.

Study Design: In vitro randomized, matched design.

Sample Population: Equine ventral median abdominal skin specimens (n = 24 horses).

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Objective: To evaluate the feasibility and repeatability of in vivo measurement of stiffness gradients by means of acoustoelastography in the superficial digital flexor tendons (SDFTs) of clinically normal horses.

Animals: 15 clinically normal horses.

Procedures: For each horse, stiffness gradient index and dispersion values for SDFTs in both forelimbs were evaluated in longitudinal orientation by use of acoustoelastography at 3 sites (5, 10, and 15 cm distal to the accessory carpal bone) by 2 observers; for each observer, data were acquired twice per site.

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Bone grafting procedures have become common due in part to a global trend of population aging. Native bone graft is a popular choice when compared to various synthetic bone graft substitutes, owing to superior biological activity. Nonetheless, the insufficient ability of bone allograft to induce new bone formation and the insufficient remodeling of native bone grafts call for osteoinductive factors during bone repair, exemplified by recombinant human bone morphogenetic protein 2 (rhBMP2).

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Objective: To determine indications for cesarean section in alpacas and llamas, and clinical management and outcome of alpacas and llamas undergoing cesarean section.

Design: Retrospective case series.

Animals: 27 alpacas and 7 llamas.

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Objectives: To determine if ovariectomy (OVE) by electrothermal bipolar vessel sealing (EBVS) is a safe alternative to ovariohysterectomy (OVH) by hand-tied ligatures as a method of spaying in pigs.

Study Design: Retrospective case series.

Animals: Intact female pigs (n = 14).

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