The aim of this study is to eveluate levels of advanced oxidation protein products (AOPP) which are thought to increase in the polyp tissue and superoxide dismutase (SOD), an antioxidant enzyme, with using specthrophotometry in polyp tissue and healthy mucosa. 30 nasal polyp patients without inflammatory disease except for nasal polyposis were included in the study. The control group consisted of 18 patients who did not have allergy, asthma, inflammatory and granulomatous disease and planned surgery due to septum deviation and concha hypertrophy.
View Article and Find Full Text PDFBackground/aim: Nasal polyposis is a chronic inflammatory disease affecting the paranasal sinuses and nasal mucosae. It is thought that genetic and molecular mechanisms in inflammatory and apoptotic pathways are the main factors in the etiopathogenesis of nasal polyposis. The aim of this study was to investigate the expression patterns of CD11b, galectin-1, beclin-1, and caspase-3 in nasal polyps.
View Article and Find Full Text PDFBackground: Nasal packing is frequently used after surgical interventions to prevent bleeding and synecchia formation and for the treatment of diseases such as epistaxis. One of the most morbid complications of nasal packing applications is the toxic shock syndrome (TSS). Owing to the microbiological structure of nasal mucosa, antibiotics are administered to all patients who are applied nasal packages for prevention of TSS.
View Article and Find Full Text PDFChoanal polyps (CPs) are unilateral benign masses usually originating from paranasal sinuses. Maxillary, ethmoid, and sphenoid sinuses are involved in order of decreasing frequency. In this study, the medical records of patients operated on with a clinical diagnosis of CP between 1998 and 2011 were reviewed.
View Article and Find Full Text PDFEpistaxis is a frequent health problem and the most common cause of emergency in otorhinolaryngology practice. In this report, a case of a 26-year-old patient with intractable epistaxis after endoscopic sinus surgery was presented. The epistaxis began at the fourth postoperative day and was unresponsive to endoscopic cauterization and anterior and posterior nasal packing.
View Article and Find Full Text PDFPurpose: Although the most common neoplastic lesion of the oral cavity is squamous cell carcinoma (SCC), primary neoplastic lesions of the hard palate have not been systematically reviewed to date. The aim of this study was to determine the histopathologic composition and characteristics of neoplasms of the hard palate.
Materials And Methods: A retrospective analysis of 66 patients with a primary neoplasm of the hard palate managed at the authors' institution from 1985 through 2012 was performed.
Kulak Burun Bogaz Ihtis Derg
March 2015
Objectives: The aim of this study was to investigate whether cyclooxygenase-2 (COX-2), arachidonate 12-lipoxygenase (ALOX12) and inducible nitric oxide synthase (iNOS) which are well-known mediators in inflammatory process play a role in nasal polyposis (NP) and to show their roles in initiation and progression of inflammation.
Patients And Methods: We investigated the expression levels of COX-2, ALOX12 and iNOS genes by real-time polymerase chain reaction (PCR) method in NP tissues obtained from 10 patients (4 females, 6 males; mean age ?? years; range 21 to 54 years).
Results: The mRNA levels of COX-2 expression observed in NP was found to be relatively increased, compared to the control tissue (p>0.
ORL J Otorhinolaryngol Relat Spec
October 2011
Purpose: The objective of this study is to show the accumulation of bile acids in laryngeal tissues of laryngeal carcinoma patients.
Materials And Methods: The present study compared the total bile acid level in the hypopharyngeal tissue, tumor tissue, and blood of 21 primary laryngeal carcinoma patients (study group) to that in the hypopharyngeal tissue and blood of 15 patients with benign laryngeal lesions (control group).
Results: The total bile acid level was significantly higher in the tumor and hypopharyngeal tissues of the study group than in the hypopharyngeal tissues of the control group; however, the difference in the blood total bile acid level between the 2 groups was not significant.
Acta Neurochir (Wien)
August 2009
Background: Various forms of intracranial air have been described in the literature.
Aim: This report aims to present clinical, radiological and intraoperative findings of a rare intracranial air entrapment case after endoscopic sinus surgery.
Aim: To describe the management of patients with elongated styloid process syndrome (Eagle's syndrome).
Materials And Methods: Sixty-one patients with elongated styloid process were treated between 2000 and 2005. Computed tomography examination defines those whose symptoms suggest the diagnosis.
Objective: To determine the relationship between primary enuresis nocturna (PEN) and obstructive upper airway problems (OUAPs).
Design: Prospective, descriptive study.
Setting: Tertiary care academic medical centre.
Radiofrequency reduction has become one of the most popular methods in the treatment of inferior nasal concha hypertrophy. During surgical treatment of inferior nasal concha hypertrophy, it is important to cause minimal injury to the overlying ciliated epithelium, since if the ciliated structure of this epithelium is permanently disrupted, it is hard to carry out one of the important functions of lining of the nasal cavity, mucociliary clearance. In this study, the ultrastructure of inferior nasal concha epithelium was examined by transmission and scanning electron microscopy in 40 patients with inferior nasal concha hypertrophy.
View Article and Find Full Text PDFKulak Burun Bogaz Ihtis Derg
February 2009
Objectives: We evaluated the use of homograft dehydrated temporal fascia (Tutoplast) in repair of tympanic membrane perforations secondary to chronic otitis media.
Patients And Methods: Dehydrated temporal fascia was used during tympanoplasty in 17 patients (10 females, 7 males; mean age 34 years; range 15 to 53 years) with chronic otitis media. Operations were type 1 tympanoplasty in six patients, tympanoplasty and mastoidectomy in three patients, and revision tympanoplasty and/or mastoidectomy in the remaining patients.
Pleomorphic adenoma (mixed tumor) is the most common benign neoplasm of the salivary glands. It is considered to occur primarily in the major salivary glands, such as the parotid and submandibular glands. It is much less common in the minor salivary glands, and rarely occurs at other sites, such as larynx, pharynx, trachea, lacrimal gland, and sinonasal tract.
View Article and Find Full Text PDFHaemangiopericytoma is an aggressive vascular tumour with a high propensity for recurrence and metastasis. It typically occurs in the soft tissues of the extremities and trunk, and is rarely seen in the oral cavity. A case of haemangiopericytoma of the hard palate is presented.
View Article and Find Full Text PDFBackground: Although some clues exist about the causative relationship of fungi and chronic rhinosinusitis, the relationship of nasal polyps and fungi has not been enlightened. The purpose of this study was to determine whether a relationship exists between fungi and massive nasal polyps and to evaluate current available diagnostic techniques for detection of fungi.
Methods: Thirty cases of massive nasal polyposis (NP) were evaluated prospectively for fungal evidence and were compared with 18 cases of concha bullosa based on direct microscopy, fungal culture, serology, polymerase chain reaction (PCR), and sequencing.
Kulak Burun Bogaz Ihtis Derg
October 2007
Objectives: We investigated the hemodynamic effects of local anesthetics with adrenaline used before septal surgery.
Patients And Methods: In a prospective, controlled design, administration of local anesthetics was performed with and without adrenaline in 39 patients and 10 patients, respectively, undergoing septal surgery. Plasma adrenaline concentrations were measured before anesthesia, and after 2, 5, and 10 minutes from anesthesia.
ORL J Otorhinolaryngol Relat Spec
September 2007
Treatment of nasal septal perforations which decrease quality of life is a surgical challenge with variable success rates. Numerous surgical methods have been proposed for closure of perforations. The technique described in this article, i.
View Article and Find Full Text PDFOral Surg Oral Med Oral Pathol Oral Radiol Endod
November 2006
Lymphangioma is a benign, hamartomatous tumor of the lymphatic system. It is usually found in the head and neck region and is widely regarded as a developmental lesion rather than a true neoplasia. Most lymphangiomas are present at birth (60%), and by the age of 2 years 80% to 90% are present.
View Article and Find Full Text PDFSphenochoanal polyp is a rare entity originating from the sphenoid sinus. It may be confused with an antrochoanal polyp on anterior rhinoscopy. Computerized tomography and nasal endoscopy have contributed to an increase of accuracy in the diagnosis of these masses.
View Article and Find Full Text PDFKulak Burun Bogaz Ihtis Derg
October 2006
Inverted papilloma is a rare benign sinonasal tumor characterized by a potentially invasive nature. The lateral nasal wall represents the most common site of origin, whereas paranasal sinuses are frequently involved by extension. In contrast, primary sinus inverted papillomas have rarely been reported.
View Article and Find Full Text PDFORL J Otorhinolaryngol Relat Spec
August 2006
Background: To investigate the accessory nerve function in lateral selective neck dissections (LSND) performed in laryngeal squamous cell carcinoma patients without dissection of level IIB.
Methods: Fifteen LSND were performed in 11 N0 laryngeal carcinoma patients with preservation of level IIB. Distal latencies, compound muscle action potentials (CMAP), and electromyography findings were investigated before surgery, during the 3rd postoperative week, and 3 months thereafter to compare the effects of the procedure on the accessory nerve.
Kulak Burun Bogaz Ihtis Derg
December 2005
A case of arteriovenous fistula (AVF) arising in the auricle was presented together with its treatment. A 20-year-old man with an AVF on the right auricle was successfully treated with superselective embolization followed by ligation of the arteries supplying the fistula. The lesion underwent considerable regression within a follow-up period of five months and no complications were encountered.
View Article and Find Full Text PDFKulak Burun Bogaz Ihtis Derg
September 2005
Objectives: To define the role of epiglottic anteversion in the etiology of globus pharyngeus (GP) and to evaluate the effectiveness of laser partial epiglottectomy in its treatment.
Patients And Methods: Four patients who admitted to our clinic between 2001 and 2003 with the complaint of GP underwent laryngoscopic examination, which revealed a structurally anteverted epiglottis that was in contact with the tongue base and vallecula. After ruling out other etiologic factors of GP, the patients were operated on under general anesthesia and laser partial epiglottectomy was carried out.
Kulak Burun Bogaz Ihtis Derg
September 2005
Objectives: To assess the rate of thyroid gland invasion and the need for thyroidectomy in advanced laryngeal and hypopharyngeal carcinomas that require total laryngectomy.
Patients And Methods: Between 1994 and 2001, 129 total laryngectomy with ipsilateral hemithyroidectomy and 14 total laryngopharyngectomy with total thyroidectomy operations were performed for primary squamous cell carcinoma of the larynx and hypopharynx. In the surgical specimens of the patients, the presence of tumor invasion to the thyroid cartilage and thyroid gland was evaluated retrospectively by light microscopic examination.