Does the intraoperative parathormone monitoring really affect surgical success in primary hyperparathyroidism?

Background: Surgery is the only curative treatment option for primary hyperparathyroidism (PHPT). The intraoperative parathormone (IOPTH) monitoring is recommended to confirm that all pathological glands have been removed. This study aimed to evaluate the effect of IOPTH monitoring on the surgical success of parathyroidectomy performed for PHPT.

External validation of the AppendistatTM score and comparison with CRP levels for the prediction of complicated appendicitis.

Background: In acute appendicitis, the treatment approach may vary depending on the age and comorbidities of the patient and whether the appendix is complicated. In this study, we validated the appendistatTM score, including the logistic regression model of complicated appendicitis, and compared the efficacy of this scoring with C-reactive protein in predicting complicated appendicitis.

Methods: Demographic characteristics, pathology, and laboratory results of patients who underwent appendectomy for acute appendicitis were retrospectively screened, those over 18 years of age were included in the study.

Differences in the Clinical Course of Acute Appendicitis in Geriatric Patient Groups.

Objective: To compare the differences in the clinical course of acute appendicitis between early elderly (60-79 years) and late elderly patients (≥80 years).

Method: The sample consisted of 177 patients aged over 60 that underwent surgery at the emergency service with the diagnosis of acute appendicitis between January 2010 and May 2018. Patients' data were retrospectively obtained from electronic records.

Peri-operative blood transfusion in elective major surgery: incidence, indications and outcome - an observational multicentre study.

Background: Patients' demographic and epidemiological characteristics, local variations in clinicians' knowledge and experience and types of surgery can influence peri-operative transfusion practices. Sharing data on transfusion practices and recipients may improve patients' care and implementation of Patient Blood Management (PBM).

Materials And Methods: This was a multicentre, prospective, observational, cross-sectional study that included 61 centres.

Associated Features with Non-Sentinel Lymph Node Involvement in Early Stage Breast Cancer Patients who Have Positive Macrometastatic Sentinel Lymph Node.

Objective: The main goal of this study is to determine the clinico-pathological factors that correlate non-sentinel lymph nodes (LNs) involvement in clinically node negative breast cancer (BC) patients with positive macrometastatic sentinel lymph node (SLN) in order to derive future evidence to define a subgroup where completion axillary lymph node dissection (cALND) might not be recommended.

Materials And Methods: Total 289 SLN biopsies were performed in clinically node negative BC patients between March 2014 and April 2017. Seventy patients who performed cALND due to positive macrometastatic SLN were retrospectively selected and classified into two groups, according to non-SLN involvement (NSLNI).

Clinical course of percutaneous cholecystostomies: A cross-sectional study.

Background: Although cholecystectomy is the standard treatment modality, it has been shown that perioperative mortality is approaching 19% in critical and elderly patients. Percutaneous cholecystostomy (PC) can be considered as a safer option with a significantly lower complication rate in these patients.

Aim: To assess the clinical course of acute cholecystitis (AC) in patients we treated with PC.

A Diagnostic Dilemma: Skip Metastasis in Papillary Thyroid Cancer.

The frequency, pattern, and predictive factors for skip LN metastasis in patients with papillary thyroid carcinoma (PTC) remain controversial. In this study, we evaluated predictive factors of skip LN metastasis in these patients. We reviewed the medical records of 68 PTC patients who underwent total thyroidectomy, central neck dissection, and lateral neck dissection at the initial operation.

Is Vocal Cord Assessment before Total Thyroidectomy Required for All Patients?

We investigated whether laryngoscopy should be performed before total thyroidectomy on all patients without a history of neck surgery. A total of 2523 patients who underwent total thyroidectomy between January 1, 2013, and March 18, 2018, were retrospectively examined. Preoperative vocal cord examination was performed on 2070 of these patients by the otorhinolaryngology department using indirect laryngoscopy.

A novel simplified scoring system for predicting mortality in emergency colorectal surgery: prediction model development.

Background: Despite advances in surgical approaches, emergency colorectal surgery has high mortality and morbidity.

Objective: We aimed to create a simple and distinctive scoring system, for predicting mortality among patients undergoing emergency colorectal surgery.

Design And Setting: Prediction model development study based on retrospective data-gathering.

External validation of anastomotic leakage risk analysis system in patients who underwent colorectal resection.

Background/aim: One of the most feared complications after colon resection for carcinoma is anastomotic leakage. Prediction of anastomotic leakage can alter pre- and perioperative management of patients. This study validates an anastomotic leakage prediction system.

A comparison of logistic regression and artificial neural networks in predicting central lymph node metastases in papillary thyroid microcarcinoma.

Objective: Prophylactic central lymph node dissection(CLND) is a controversial issue in papillary thyroid microcarcinoma( PTMC) patients without lymphatic metastasis. Artificial neural network(ANN) has been proposed as an alternative statistical technique for predicting complex biologic phenomena. Our aim is to develop an ANN model in predicting central lymph node metastases(CLNM) in patients with PTMC, in comparison to traditional logistic regression(LR) analysis.

Can we predict severity of acute cholecystitis at admission?

Background And Objective: Acute cholecystitis (AC) is an inflammation of the gallbladder. Tokyo Guidelines (TGs) for the diagnosis of AC classified this condition according to severity as mild, moderate and severe. Therapeutic intervention regulated according to the type of severity.

Long-term results of patients who were applied laparoscopic adjustable gastric banding.

Objectives: The most effective treatment step in morbid obesity is surgical treatment. The purpose of the present study was to investigate the long-term follow-up results and success rates in patients who were applied laparoscopic adjustable gastric band.

Material And Methods: The change in body mass index, percentage of excess weight loss, comorbidities, and resulting complications were investigated in 220 patients who were morbidly obese who were applied laparoscopic adjustable gastric band between April 2006 and February 2012 throughout the 6-year follow-up period.

Long-term results of the patients who were applied laparoscopic adjustable gastric banding.

Objectives: The most effective treatment step in morbid obesity is surgical treatment. The purpose of the present study was to investigate the long-term follow-up results and success rates in laparoscopic adjustable gastric banding.

Material And Methods: The change in body mass index, percentage of excess weight loss, comorbidities, and resulting complications were investigated in 220 patients who were morbidly obese and applied laparoscopic adjustable gastric band between April 2006 and February 2012, throughout the 6-year follow-up period.

Simplified scoring system for prediction of mortality in acute suppurative cholangitis.

Our objective in this study was to identify the factors contributing to mortality in acute suppurative cholangitis which could be tested easily in every emergency clinic. This is a retrospective study enrolling 104 patients with acute suppurative cholangitis. Demographic and laboratory data were collected for analysis.

A rare cause of primary hyperparathyroidism: Parathyroid lipoadenoma.

Objective: The main cause of primary hyperparathyroidism is a single parathyroid adenoma. Parathyroid lipoadenomas contain abundance of fat cells. Because of these histological features, they can mimic normal parathyroid tissue at the histopathologic examination and radiological imaging could be difficult to localize lipoadenomas.

Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection.

Aim: To evaluate the prognostic significance of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and prognostic nutritional index (PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer.

Methods: 183 patients with histologically proven colorectal cancer who had undergone potentially curative resection between 2010 and 2016 at Ankara Numune Training and Research Hospital were retrospectively analyzed and clinicopathological characteristics included age, sex, tumor type, grade, size and localization, the number of metastatic and total number of lymph nodes removed, vascular and perineural invasion of the tumor, TNM stages, tumor marker levels (CEA, CA19-9, AFP, CA-125, CA15-3), complete blood counts, albumin levels, overall survival (months), NLR, PLR, LMR and PNI ratios were retrospectively reviewed and analyzed from the electronic database. The primary outcome measure was overall survival.

Clinical course of incidental parathyroidectomy: Single center experience.

Objective: Thyroidectomy is a very common surgical procedure. Regardless of surgeon experience, incidental parathyroidectomy is a complication of thyroidectomy. The aim of this study was to identify the clinical course of incidental parathyroidectomies after thyroidectomy.

The prognostic value of different node staging systems in patients with ≤15 lymph nodes following surgery for gastric adenocarcinoma.

Aim: Lymph node (LN) status is an important prognostic indicator in patients with gastric cancer (GC). Although American Joint Committee on Cancer/International Union against Cancer (AJCC/UICC) is the most widely used staging system, there is a challenge in predicting survival of patients when the number of total harvested LNs is ≤15. Our aim was to investigate the prognostic performances of seventh edition AJCC/UICC, lymph-node ratio (LNR), and log odds of metastatic lymph nodes (LODDS) on the overall survival (OS) of GC patients with ≤15 examined LNs after gastric resection.

Concomitant thyroid cancer in patients with primary hyperparathyroidism in an endemic goitre region.

Objective: Primary hyperparathyroidism (pHPT) is often accompanied by underlying thyroid pathology and 1 to 36% of these thyroid pathologies are malignant. How the identification of these lesions affects patient management is unclear. We present a single-center experience with the prevalence of concomitant thyroid cancer in patients who underwent parathyroidectomy for pHPT.